Publications by authors named "C Ayoub Moubareck"
Epidemiology and antimicrobial resistance of spp. in the United Arab Emirates: a retrospective analysis of 12 years of national antimicrobial resistance surveillance data.
Front Public Health
July 2024
Article Synopsis
- * A 12-year study in the UAE analyzed over 8,000 non-duplicate MTB complex isolates, primarily from respiratory samples, revealing that most patients were non-nationals from Asian countries, particularly India and Pakistan.
- * The study found low levels of drug resistance, with 2.8% of MTB isolates being rifampicin-resistant and a slight upward trend in resistance observed over the years.
Objectives: To evaluate literature from a 12-year period (2010-2021) on the antimicrobial resistance profile of Pseudomonas aeruginosa from the Arabian Gulf countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates).
Methods: An electronic literature search was conducted for articles on antimicrobial resistance in P. aeruginosa and associated phenotypes, covering the period of 1st January 2010 to 1st December 2021.
Article Synopsis
- * A 12-year surveillance study in the UAE (2010-2021) revealed an upward trend in antimicrobial resistance, with data showing that most cases came from inpatient settings, particularly affecting isolates from urine, blood, and respiratory tracts.
- * The study found high resistance rates to common antifungals, with notable increases in echinocandin resistance, although mortality rates did not differ significantly between resistant and non-resistant patients.
Introduction: is a group of ubiquitous non-fermenting Gram-negative bacteria (NFGNB). Of the several species associated with humans, (PA) can acclimate to diverse environments. The global frequency of PA infections is rising and is complicated by this organism's high intrinsic and acquired resistance to several clinically relevant antibiotics.
View Article and Find Full Text PDFArticle Synopsis
- Enterococci typically cause mild infections but can lead to serious diseases like urinary tract infections and meningitis, with rising antibiotic resistance posing significant health threats, especially in the MENA and Gulf regions where data is limited.
- A 12-year retrospective study analyzed over 37,000 bacterial isolates from the UAE, revealing that Enterococcus faecalis was the most common species found, with 1.8% showing vancomycin resistance (VRE), notably higher in Enterococcus faecium.
- The presence of VRE is linked to increased patient mortality and longer hospital stays, highlighting the need for more awareness and surveillance of antibiotic resistance in the region.