Tuberculin skin testing in intravenous drug users: differences between HIV-seropositive and HIV-seronegative subjects.

The prevalence of tuberculin skin test reactions among intravenous drug abusers and differences in tuberculin skin test positivity between HIV-seropositive and HIV-seronegative subjects were evaluated in a cross-sectional study of 1131 subjects. They were recruited from a therapeutic community, from those who attended the centre for the treatment of drug addiction and from those who visited for any reason an acute tertiary-care hospital in Vitoria-Gasteiz, Basque Country (Spain). All subjects underwent skin testing with purified protein derivative (PPD) tuberculin and testing for HIV antibodies.

[Tuberculin test in HIV infection].

Background: Intravenous infected-HIV drug abusers (IDAP/HIV+) are known to have a higher risk of tuberculosis (TB) than others. The effectiveness of tuberculin testing (Mantoux) in the detection of the TB infection in HIV(+) patients is probably lower than HIV(-) individuals. The aim of this paper is to assess tuberculin testing in the active search of cases of TB infection in IDAP individuals and their differences between HIV(+) and HIV(-) ones.

[Intrasplenic pseudocyst and ascites as complications of exacerbated chronic pancreatitis].

A patient with chronic alcoholism displayed significant ascites and a splenic pseudocyst, after relapsing chronic pancreatitis. The pathogenic possibilities are commented. The break of pancreatic ducts, with extravasation of enzymes, that would reach adjacent structures, is a common mechanism to both complications.