Publications by authors named "C Asher"
Article Synopsis
- Mind The Bleep (MTB) is an online educational platform run by UK resident doctors, focusing on providing free surgical education resources for early postgraduate doctors, especially during the COVID-19 pandemic.
- The study assessed MTB's teaching methods using a mix of quantitative and qualitative data, including participant feedback and website analytics, analyzing 22 educational programs and 140 webinars conducted between 2021 and 2024.
- Results showed significant increases in participant confidence (p<0.05) and highlighted the effectiveness of a near-peer teaching model, although limitations included a low feedback response rate and limited types of feedback collected.
This novel case documents the successful use of transcatheter aortic valve implantation to treat severe aortic insufficiency arising from aortic root dissection following the repair of an ascending aortic aneurysm in a 75-year-old female patient. After she presented with symptoms of congestive heart failure, investigation revealed new severe aortic insufficiency and an acute aortic dissection. Given the prohibitive risks of reoperation, a self-expanding 27-mm Portico (St Jude Medical) prosthetic aortic valve was deployed, resulting in substantial clinical improvement without procedural complications.
View Article and Find Full Text PDFPericardial diseases have gained renewed clinical interest, leading to a renaissance in the field. There have been many recent advances in pericardial diseases in both multimodality cardiac imaging of diagnoses, such as recurrent, transient constrictive and effusive-constrictive pericarditis, and targeted therapeutics, especially anti-interleukin (IL)-1 agents that affect the inflammasome as part of autoinflammatory pathophysiology. There remains a large educational gap for clinicians, leading to variability in evaluation and management of these patients.
View Article and Find Full Text PDFAims: Hypertensive patients of African ancestry (Afr-a) have higher incidences of heart failure and worse clinical outcomes than hypertensive patients of European ancestry (Eu-a), yet the underlying mechanisms remain misunderstood. This study investigated right (RV) and left (LV) ventricular remodelling alongside myocardial tissue derangements between Afr-a and Eu-a hypertensives.
Methods And Results: 63 Afr-a and 47 Eu-a hypertensives underwent multi-parametric cardiovascular magnetic resonance.
Article Synopsis
- Mavacamten is approved for treating symptomatic obstructive hypertrophic cardiomyopathy (oHCM) and aims to improve left ventricular outflow tract gradients and reduce the need for septal reduction therapy (SRT).
- A study of 150 patients showed significant improvements in New York Heart Association (NYHA) class and reduced LVOT gradients after 12 weeks of mavacamten treatment, with 46% of patients showing at least one class improvement.
- Although there was a slight decline in left ventricular ejection fraction (LVEF), no patients required SRT or experienced severe heart failure complications during the study period.