It has been suggested that Merkel Ranvier cells, generally considered as belonging to the Apud system, may be the origin of extremely rare skin tumors. The authors analyse the characteristics of an apudoma in connexion with a case, and compare their findings with those of 58 other cases reported in the literature. With light microscopy techniques, the differential diagnosis is essentially one of a non-differentiated primary or secondary carcinoma, or of a lymphosarcoma.
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