Publications by authors named "C Arens"

This CME article explores the evolving role of endosonography in otorhinolaryngology and head and neck surgery. Endosonography offers significant potential to improve imaging inside the upper respiratory tract, particularly with advancements in probe technology and imaging resolution. The article will describe the sonoanatomy of the oral cavity, pharynx, and larynx and the selection of probes and scanning techniques used for the various anatomical sites.

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Objectives: With over 184,000 new cases and more than 99,000 deaths per year, malignancies of the larynx are a global health problem. Currently, a dedicated screening method enabling a direct onsite diagnosis is missing. This can lead to delayed diagnosis and worse outcomes of the patients.

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Article Synopsis
  • A study referred to as SUPRATOL investigated the effects of transoral laser microsurgery for supraglottic laryngectomy, comparing its outcomes for swallowing and quality of life to traditional open surgery, revealing similar oncologic results but limited data on swallowing rehabilitation and QoL before this trial.
  • The trial included 102 patients across 26 hospitals in Germany, with the main goal of measuring aspiration-free swallowing after one year and exploring various related factors such as tracheostomy needs and overall survival.
  • Results showed high rates of aspiration-free swallowing at the 12-month mark, with a majority of patients still managing well with swallowing, although some required tracheostomy and PEG tube interventions, indicating mixed results on QoL
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Background: Highflow nasal cannula oxygen (HFNO) is known to be used for noninvasive oxygenation in intensive care patients but it has rarely been used in airway management for elective surgery of the upper aerodigestive tract.

Objectives: HFNO offers opportunities of a tubeless oxygenation system which is easy to handle and not limited only on surgery of the endolarynx.

Methods: We evaluated this method for oxygenation during brief interventional procedures of the larynx and pharynx in 92 adult patients for safety and intraoperative complications.

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Different studies suggest an impact of biofilms on carcinogenic lesion formation in varying human tissues. However, the mechanisms of cancer formation are difficult to examine in vivo as well as in vitro. Cell culture approaches, in most cases, are unable to keep a bacterial steady state without any overgrowth.

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