Publications by authors named "C Aracil"
Background And Aims: Data on the effectiveness of classical non-selective beta-blockers (cNSBB, i.e., propranolol and nadolol) versus carvedilol in patients with cirrhosis are scarce.
View Article and Find Full Text PDFHemodynamic effects of carvedilol plus simvastatin in cirrhosis with severe portal hypertension and suboptimal response to β-blockers: A double-blind, placebo-controlled, randomized-trial.
Hepatology
November 2024
Background Aims: Carvedilol is a non-selective β-blocker (NSBBs) with anti-α1-adrenergic activity, more effective than traditional NSBBs in reducing portal-pressure (HVPG). However, 35%-45% of patients still have insufficient HVPG-decrease. Statins ameliorate endothelial dysfunction, reduce hepatic vascular resistance, and have pleiotropic effects.
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- Brain plasticity varies after multistep surgery for low-grade gliomas, and personalized neurosurgical approaches using functional imaging can enhance recovery outcomes.
- A study involving four patients with left frontal low-grade gliomas near the supplementary motor area complex (SMAC) showed that surgical interventions did not result in permanent neurological deficits, and some patients exhibited new activity in the right hemisphere after left-side resection.
- The findings suggest SMAC operates as a flexible cortico-subcortical network that can reorganize to compensate for neurological deficits, emphasizing the role of the left middle frontal gyrus in this process.
Background And Aims: Spontaneous ruptured hepatocellular carcinoma is an uncommon complication, and there are scarce data about non-cirrhotic patients. Tumor treatment is not standardized and the risk of peritoneal dissemination is unclear.
Aim: we analyzed the treatment and survival in patients with rHCC on non-cirrhotic liver.
Background & Aims: Bleeding from gastric fundal varices (isolated gastric varices type 1/gastroesophageal varices type 2) represents a major problem because of a high incidence of rebleeding and death with standard-of-care therapy (endoscopic obliteration with tissue adhesives plus pharmacological therapy). Transjugular intrahepatic portosystemic shunts (TIPSs) are recommended as a rescue therapy. Pre-emptive 'early' TIPS (pTIPS) significantly improves control of bleeding and survival in patients at high-risk of dying or rebleeding from esophageal varices.
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