The effects of isoproterenol (IPNA) on global and regional left ventricular wall motion were studied by cardiac angioscintigraphy at equilibrium performed under basal conditions, during IPNA administration (per IPNA) and 10 minutes after (post IPNA) in 50 patients classified by coronary angiography as coronary (C) (n = 37) and non-coronary (NC) patients (n = 13), 5 reference subjects (REF) and 8 non-coronary pathology. The effects were assessed from variations of global LV function and from indices of regional wall function (12 regional ejection fractions - REF). The IPNA perfusion was well tolerated, even in patients with severe coronary lesions.
View Article and Find Full Text PDFCardiac angioscintigraphy at equilibrium was performed after in vitro red cell labelling in the left anterior oblique and anterior views. A syringe of 10 ml labelled blood was placed on the patient's chest over the left ventricle and in contact with the camera's collimator in the LAO incidence. This syringe plays a dual part: as a direct reference for left ventricular radio-activity and as a marker for measuring the distance between the centre of gravity of the LV and the collimator by Links' method.
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