Publications by authors named "C Andrew"

The two-week Home Base Intensive Clinical Program (ICP) provides treatment to veterans and active duty service members suffering from primary diagnoses of posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), anxiety, or depression. First launched in 2015, this paper provides a programmatic update, including new treatment components implemented since inception, and examines outcomes for all participants who entered the program from September 2015 to July 2024 ( = 2561). The Home Base ICP provides a massed care approach through daily individual Prolonged Exposure, Cognitive Processing Therapy, Unified Protocol, or cognitive rehabilitation, along with groups targeting coping skills.

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  • Diffusion-weighted imaging (DWI) measures the motion of water protons in fetal tissues, notably assessing the apparent diffusion coefficient (ADC) values for various fetal organs and the placenta at different gestational ages.
  • The study included 103 singleton pregnancies from 20 to 38 weeks and used specific imaging parameters to evaluate ADC values in areas like the fetal brain, lungs, kidneys, and placenta.
  • Results showed significant variances in ADC values across brain regions and a positive correlation between white matter ADC values and gestational age, while no significant correlation was found for kidneys.
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Background: It has been hypothesised that frailty is the root cause of clinically observed but rarely systematically measured unstable disability among older adults. In this study, we measure the extent of short-term disability fluctuations and estimate their association with frailty using intensive longitudinal data.

Methods: Repeated measurements of disability were collected under a measurement burst design in the FRequent health Assessment In Later life (FRAIL70+) study.

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  • The study investigates how ongoing maternal depressive symptoms in the first three months postpartum affect infant neurodevelopment at six months old.
  • Researchers followed 1,253 mother-infant pairs and found that 7.5% of mothers experienced persistent depression, and similarly, 7.5% of infants showed neurodevelopmental delays.
  • Infants of mothers with persistent depressive symptoms had a much higher risk of neurodevelopmental delay (48.6%) compared to those without (5.1%), indicating a significant negative impact of maternal mental health on infant development.
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