Febrile Convulsion among Hospitalized Children Aged Six Months to Five Years and Its Association With Haemoglobin Electrophoretic Pattern.

Background: Febrile convulsion and sickle cell disease are common in tropical countries and both are associated with significant morbidity and mortality. Worldwide, Nigeria has the highest prevalence of sickle cell disease. However, there is a dearth of knowledge on the haemoglobin electrophoresis in patients with febrile convulsions.

5 Year old girl with malignant lymphoblastic lymphoma: challenges of managing haematological malignancies in a developing country.

Background: Lymphoblastic lymphoma (LBL) is a neoplasm of lymphoblasts. The condition is predominantly lymph node-based disease arising from immature T cells in 85-90% of cases and immature B cells in the remainder. The lymphoma is aggressive, progresses rapidly, and often presenting as stage IV disease in more than 70% of patients.

A re-appraisal of warfarin control in the treatment of deep vein thrombosis and / or pulmonary embolism.

Background: Warfarin is commonly used for management of deep vein thrombosis (DVT) and pulmonary embolism (PE), controlling therapy by means of the International Normalized Ratio (INR).

Objectives: To identify differences in INR results between patients with thromboembolic and haemorrhagic complications and controls.

Methods: Two nested case-control studies from within a controlled trial of the duration of warfarin therapy (47 thrombotic and 16 haemorrhagic complications).

Re-evaluation of methaemoglobin reduction as a screening procedure for glucose-6-phosphate dehydrogenase (G6PD).

Methaemoglobin reduction method is considered to be an old method of qualitative analysis of glucose-6-phosphate dehydrogenase with low specificity and sensitivity and as such, many are sceptical about the reliability of the outcome of the result of the methodology.The aims of this study were to determine the sensitivity and specificity of methaemoglobin reduction method and examine its suitability as a routine method for the screening of glucose-6-phosphate dehydrogenase in this environment. One hundred children were recruited into the study which was conducted over a period of one year.