Publications by authors named "C Ai-Vyrn"
Article Synopsis
- The AGELESS Trial was a study in Malaysia to see if a special program could help older adults with cognitive frailty, which is a risk for dementia.
- They wanted to learn about the people who joined the study to understand better who is at risk and willing to take part.
- The trial included 957 older adults, with about 39% having cognitive frailty, showing that these participants often had less education and lower cognitive abilities.
Background: The global population is ageing rapidly, with the most dramatic increases in developing countries like Malaysia. Older people are at increased risk of multimorbidity, frailty and falls.
Objectives: In this study we aimed to determine the relationship between social participation, frailty and falls in Malaysia.
Background: Cognitive frailty (CF) is identified as one of the main precursors of dementia. Multidomain intervention has been found to delay or prevent the onset of CF.
Objective: The aim of our present study is to determine the effectiveness of a comprehensive, multidomain intervention on CF; to evaluate its cost effectiveness and the factors influencing adherence toward this intensive intervention.
Background: The incidence of Alzheimer's disease, particularly in developing countries, is expected to increase exponentially as the population ages. Continuing research in this area is essential in order to better understand this disease and develop strategies for treatment and prevention. Genome-wide association studies have identified several loci as genetic risk factors of AD aside from apolipoprotein E such as bridging integrator (BIN1), clusterin (CLU), ATP-binding cassette sub-family A member 7 (ABCA7), complement receptor 1 (CR1) and phosphatidylinositol binding clathrin assembly protein (PICALM).
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