Publications by authors named "C Ahlgrim"
Aims: To quantify greyzone fibrosis (GZF) in patients after acute myocardial infarction (MI) and to evaluate its correlation with MI-free survival and improvements in left ventricular ejection fraction (LVEF) compared with the established risk factors high-sensitivity cardiac troponin T (hs-cTnT) and Late Gadolinium Enhancement (LGE).
Methods And Results: The study involved 176 patients who experienced acute MI and underwent cardiac magnetic resonance (CMR) prior to hospital discharge, followed by a second CMR on average six months later. LGE was quantified in both examinations, a separate analysis of the GZF was conducted only in the follow-up CMR after resolution of the initial infarct edema.
In chronic heart failure, dilutional anemia and hypervolemia may occur due to plasma volume expansion, the latter sometimes exacerbated by an increase in red cell volume. Diagnosis and a therapeutic strategy require determination of vascular volumes.
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- The study examines how blood volume (BV) per kg of body mass (BM) may underestimate BV in individuals with high fat mass, particularly highlighting differences between sexes, ages, and fitness levels.* -
- It was found that women had a lower BV/BM compared to men by 25%, but when adjusted for lean body mass (LBM), women showed a 6% higher BV/LBM.* -
- Among athletes, BV/BM was 17.2% higher than non-athletes, but this difference shrank to only 2.5% when adjusted for LBM, indicating that LBM is a strong predictor of BV and hemoglobin mass (Hb) in clinical assessments.*
Aim: This study sought to develop and validate diagnostic models to identify individuals with atrial fibrillation (AF) using amplified sinus-p-wave analysis.
Methods: A total of 1,492 patients (491 healthy controls, 499 with paroxysmal AF and 502 with persistent AF) underwent digital 12-lead-ECG recording during sinus rhythm. The patient cohort was divided into training and validation set in a 3:2 ratio.
Background: Progressive atrial fibrotic remodeling has been reported to be associated with atrial cardiomyopathy (ACM) and the transition from paroxysmal to persistent atrial fibrillation (AF). We sought to identify the anatomical/structural and electrophysiological factors involved in atrial remodeling that promote AF persistency.
Methods: Consecutive patients with paroxysmal ( = 134) or persistent ( = 136) AF who presented for their first AF ablation procedure were included.