Publications by authors named "C Agudelo"

Article Synopsis
  • Sleep disordered breathing (SDB) is a risk factor for stroke and Alzheimer’s disease, particularly among Hispanic/Latino adults, highlighting the need for research on its impact on brain health in this demographic.
  • This study, based on the Hispanic Community Health Study, analyzed the association between SDB and brain MRI measures in a diverse group of Hispanic/Latino adults, using data from 2,667 participants with neuroimaging conducted about 10 years after initial sleep assessments.
  • Results indicated that higher respiratory event index (REI) correlated with larger hippocampal volumes, while lower oxygen levels during sleep were related to expanded white matter hyperintensity (WMH) volumes, suggesting complex relationships between SDB, oxygen
View Article and Find Full Text PDF

Infected macrophages transition into aerobic glycolysis, a metabolic program crucial for control of bacterial infection. However, antimicrobial mechanisms supported by aerobic glycolysis are unclear. Methylglyoxal is a highly toxic aldehyde that modifies proteins and DNA and is produced as a side-product of glycolysis.

View Article and Find Full Text PDF
Article Synopsis
  • Systemic lupus erythematosus (SLE) is a rare autoimmune disease affecting multiple organs, and it's even rarer for it to coexist with Giant Cell Arteritis (GCA).
  • The case presented involves a 56-year-old woman whose main symptom was chest pain; imaging confirmed the diagnosis while excluding other conditions like Takayasu arteritis.
  • She was treated with glucocorticoids and tocilizumab, which led to a good recovery, highlighting the importance of accurate diagnosis to avoid serious complications.
View Article and Find Full Text PDF

Although human immunodeficiency virus (HIV)-associated arthropathy is the most frequently described joint syndrome, the spectrum of its clinical manifestations is poorly known, and it is difficult to distinguish it from reactive arthritis (ReA). Knowing how to differentiate these two conditions has major implications regarding their prognosis and treatment. We present the case of an adult patient with a history of HIV infection with adequate virological control and good adherence to antiretroviral treatment, which began with an acute clinical picture consisting of additive asymmetric oligoarthritis with subsequent transition to symmetric polyarthritis predominantly in the upper extremities, initially attributed to ReA.

View Article and Find Full Text PDF

Organic micropollutants (OMPs) present in water and wastewater are in the spotlight because of their potentially harmful effects even at low concentrations and the difficulties of their elimination in urban wastewater treatment plants (UWWTPs). This study explores the impact of some membrane filtration processes on the removal of a group of 11 OMPs with an eye on the effects of two pretreatments (i.e.

View Article and Find Full Text PDF