Introduction: We investigated whether depression modified the associations between sleep duration and cognitive performance.
Methods: Multivariable linear regression models examined the associations between sleep duration and cognition in 1,853 dementia- and stroke-free participants from the Framingham Heart Study. Participants were categorized in four groups: no depressive symptoms, no antidepressants; depressive symptoms without antidepressants use; antidepressant use without depressive symptoms; both depressive symptoms and antidepressant use.
Objective: A high office blood pressure (BP) is associated with cognitive decline. However, evidence of 24-h ambulatory BP monitoring is limited, and no studies have investigated whether longitudinal changes in 24-h BP are associated with cognitive decline. We aimed to test whether higher longitudinal changes in 24-h ambulatory BP measurements are associated with cognitive decline.
View Article and Find Full Text PDFMicroservices is an architectural style for service-oriented distributed computing, and is being widely adopted in several domains, including autonomous vehicles, sensor networks, IoT systems, energy systems, telecommunications networks and telemedicine systems. When migrating a monolithic system to a microservices architecture, one of the key design problems is the "microservice granularity definition", ., deciding how many microservices are needed and allocating computations among them.
View Article and Find Full Text PDFBackground: Twenty-four-hour and nighttime blood pressure (BP) levels are more strongly associated with cardiovascular risk than office or daytime BP measurements. However, it remains undocumented which of the office and ambulatory BP measurements have the strongest association and predictive information in relation to the presence of type I, or arteriolosclerosis type, cerebral small vessel diseases (CSVD).
Methods: A subset of 429 participants from the Maracaibo Aging Study [aged ≥40 years (women, 73.