PurposeChimeric antigen receptor (CAR) T-cell CD19 therapy has changed the treatment paradigm for patients with relapsed/refractory B-cell acute lymphoblastic leukemia. It is frequently associated with potentially severe toxicities: cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS), and admission to PICU is often required. Some biomarkers seem to correlate with CRS severity.
View Article and Find Full Text PDFEquine piroplasmosis is a worldwide tick-borne disease caused by the parasites Theileria equi sensu lato and Babesia caballi, with significant economic and sanitary consequences. These two parasites are genetically variable, with a potential impact on diagnostic accuracy. Our study aimed to evaluate the frequency of asymptomatic carriers of these parasites in France and describe the circulating genotypes.
View Article and Find Full Text PDFInt J Health Plann Manage
January 2025
Health care is changing rapidly. Hospitals are, and will remain, an essential setting to deliver it. We discuss how to maximise the benefits of hospitals in the future in different geographic and health system settings, highlighting a series of cross-cutting issues.
View Article and Find Full Text PDFAim: The aim of this research is to analyse and assess the anatomical variability of the infraorbital canal, groove, and foramen using high-resolution CT images of the Indian population using mimics software.
Materials And Methods: A total of 100 high-resolution CT (HRCT) data (200 hemi-faces) with a range of 18-65 years in Digital Imaging and Communication in Medicine (DICOM) format was incorporated in mimics software. Infraorbital foramen (IOF), infraorbital groove (IOG), and infraorbital canal (IOC) were evaluated retrospectively using seven parameters.
Regular occurrences of oil leaks are recognized as a significant contributor to water pollution, resulting in substantial environmental and ecological challenges, as well as posing potential for fires and explosions. Therefore, it is imperative to create a cost-effective and exceptionally effective absorbent material for separating oil and water. Hydrophobic, foam-like materials have garnered considerable attention as potential absorbers for addressing oil spills and recovering oil from water sources.
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