Publications by authors named "C A Walker"
Being raised under adverse conditions during infancy and childhood represents a significant risk factor for developing later psychopathologies and dysfunctions in emotional, affective, and cognitive abilities. Depending on the type, timing, and duration of early adversity, different consequences emerge across the sexes in both human and animal models, although our understanding of the underlying interactions between sex and early life stress (ELS) is still incomplete. In this study, we used the limited bedding (LB) paradigm, a well-described model of ELS in rat pups during the first 10 days of life, and tested whether masculinization of the female brain by neonatal injections of estradiol benzoate (EB) would recapitulate the ELS-induced vulnerability phenotype of males on morphology of the basolateral amygdala (BLA) principal neurons and pre-adolescent and adult behavior.
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- The study aimed to assess the risk of reoperation in patients with spine deformities undergoing major surgeries from the thoracic to pelvis region over a 10-year period, using a large dataset.
- Out of 7,062 patients, the overall reoperation rate was found to be 23.2%, with specific rates of 16.9% at 2 years and 22.1% at 5 years; factors like preoperative kyphosis and extensive instrumentation were linked to higher risk.
- Key findings indicated that using interbody cages reduced reoperation risk, while age, medical conditions, and the presence of osteotomies did not significantly affect outcomes.
The blood flow-detecting mode of ultrasound images can be beneficial for assessing the degree of inflammation among various musculoskeletal conditions and their recovery. Power Doppler (PD) ultrasound is typically used for blood flow, but its limitations in detecting low-velocity blood flow hinder comprehensive assessment. The microvascular flow tool (MV-Flow) from the Samsung V7 and RS85 ultrasound systems (Samsung Co.
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