Publications by authors named "C A Tilley"

Article Synopsis
  • * Traditional pain management methods, including NSAIDs, opioids, and other medications, have shown limited effectiveness in alleviating lymphatic pain.
  • * The review aims to enhance understanding of lymphatic pain through research-based insights, emphasizing the importance of precise pain assessment and innovative behavioral interventions to improve treatment outcomes.
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Article Synopsis
  • A study aimed to assess how the timing of intubation affects mortality rates in severely ill COVID-19 patients, given the ongoing uncertainty about the best intubation practices.
  • The research was conducted at ten academic hospitals in the U.S. and Europe from early 2020 to late 2022, focusing on adults hospitalized specifically for COVID-19 who needed intubation.
  • Results showed that patients intubated early (less severe symptoms) had a 32% lower risk of dying within 30 days compared to those intubated later (more severe symptoms), suggesting early intervention might be more beneficial.
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Purpose: The purpose of this study was to examine the impact of co-occurring symptoms in patients with advanced cancer and malignant fungating wounds (MFWs) on palliative and functional performance, and the feasibility of collecting self-reported data in this population.

Design: This was an exploratory, observational study. Quantitative surveys and qualitative semistructured interviews using a phenomenological approach were employed.

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Article Synopsis
  • Externalizing disorders (ED) are a significant public health issue with strong genetic links, making genes like ADGRL3 important for study.
  • Research using adgrl3.1 zebrafish highlighted behavioral traits such as high impulsivity, risk-taking, and hyperactivity, which are typical of ED.
  • Atomoxetine can alleviate these behaviors, indicating a role of noradrenergic systems, while brain studies reveal new genetic pathways that may contribute to understanding and treating ED.
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