Intrauterine Therapy.

Since the first intrauterine interventions were carried out in the 1970 s under what today would be considered basic conditions, the range of prenatal interventions has steadily expanded, as has the frequency with which these interventions are carried out at specialized centers. Although most of these procedures are minimally invasive, they are invariably associated with considerable risks for the fetus and, depending on the surgical method, also for the expectant mother. For this reason, most centers worldwide limit themselves to interventions for fetal diseases which, if untreated, have a fatal course or experience a significant deterioration in the postnatal prognosis during the course of intrauterine development.

Facilitators and barriers to implementing smoke-free homes in Armenia: a qualitative study.

Smoke-free homes (SFHs) reduce secondhand smoke exposure (SHSe), which is particularly crucial where smoking prevalence is high and public smoke-free policies are nascent, as in some low- and middle-income countries (LMICs). This study examined perspectives regarding SFHs, including barriers and facilitators, among adults in Armenia, a LMIC with high male smoking prevalence and recently-implemented smoke-free policies. In February-March 2024, focus groups were conducted with adults reporting smoking and non-smoking, separately, in two Armenian communities ( = 39; = 41.

Ongoing outbreak of maternal parvovirus B19 infections in Germany since end of 2023: consequence of COVID-19 pandemic?

Objective: To investigate the ongoing parvovirus B19 (B19V) outbreak among pregnant women in Germany and its connection to the coronavirus disease 2019 (COVID-19) pandemic.

Methods: This retrospective cohort study analyzed anonymous data regarding serologically confirmed B19V infections during pregnancy between January 2014 and April 2024 across 13 major fetal medicine centers in Germany. We evaluated the yearly frequency of B19V cases, cases that underwent intrauterine transfusion (IUT), cases presenting with hydrops fetalis and cases of intrauterine fetal death (IUFD) related to B19V infection, and stratified these variables by event occurrence < 20 weeks' gestation or ≥ 20 weeks' gestation.

Sonographic diagnosis of fetal eye anomalies and their association with syndromal diseases: A retrospective multicenter analysis of 264 cases.

Introduction: This study aims to systematically describe eye malformations and correlate these with extraocular findings. Based on these findings, we propose a protocol for ultrasound evaluation of the fetal eye.

Material And Methods: In this multicentric retrospective cohort study, 264 fetuses with ocular malformations from two tertiary referral centers for prenatal medicine were analyzed.

Fast whole brain relaxometry with Magnetic Resonance Spin TomogrAphy in Time-domain (MR-STAT) at 3 T: a retrospective cohort study.

Objective: To report T/T-values of normal and normal appearing brain tissues (NBTs, healthy volunteers; NABTs, patients) acquired with a whole-brain 5-minute Magnetic Resonance Spin TomogrAphy in Time-domain (MR-STAT) protocol, and to explore relaxometry behavior in a brain tumor and in a multiple sclerosis patient.

Methods: MR-STAT was acquired in 49 participants (39 patients with neurological pathologies, age range: 21-79 years) at 3 T. Mean T/T-values were computed for: normal and normal appearing grey matter (NGM/NAGM)/white matter (NWM/NAWM)/thalamus/putamen/caudate nucleus (CN)/globus pallidus (GP).