Method validation studies characterize the performance of new laboratory methods relative to established methods using quality guidelines in order to define the new method's performance characteristics and to identify differences that could influence data interpretation. We investigated the performance of an in-clinic dry chemistry analyzer (Catalyst One, IDEXX) for measuring 19 routine plasma biochemistry analytes in dogs, cats, and horses. We analyzed 2 levels of quality control material (QCM) in duplicate twice daily for 5 d to determine the coefficient of variation (CV), percent bias, observed total error (TE), and sigma metric (σ) for each analyte at each level of QCM.
View Article and Find Full Text PDFThis study evaluated the quality and bacteriologic safety of platelet-rich plasma (PRP) produced by 3 simple, inexpensive tube centrifugation methods and a commercial system. Citrated equine blood collected from 26 normal horses was processed by 4 methods: blood collection tubes centrifuged at 1200 and 2000 × g, 50-mL conical tube, and a commercial system. White blood cell (WBC), red blood cell (RBC), and platelet counts and mean platelet volume (MPV) were determined for whole blood and PRP, and aerobic and anaerobic cultures were performed.
View Article and Find Full Text PDFThe Purpose in Life and Seeking Noetic Goals tests were administered to 198 rural Missouri and 659 metropolitan-area Washington high school students and readministered after an 8-week interval. The obtained test-retest and Cronbach alpha coefficients were largely consistent with earlier research using adult clinical samples.
View Article and Find Full Text PDFThe performances of 49 brain-injured community college students (41% women; M age = 34.0 yr., SD = 13.
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