Publications by authors named "C A Sabin"
Introduction: Depressive symptoms are highly prevalent among people with HIV, which can negatively impact HIV-related outcomes. We explore the cascade of mental healthcare for people with HIV experiencing depressive symptoms.
Methods: People with HIV who were part of the Pharmacokinetic and clinical Observations in PeoPle over fiftY (POPPY) study (2013-2016) were included.
Objectives: Our objective was to explore how women living with HIV aged ≥40 years perceive their care in relation to their HIV infection, comorbidities, and menopausal health and to evaluate the extent to which the care they receive meets their expectations, comparatively across World Health Organization (WHO) European regions.
Methods: We conducted a cross-sectional survey (May-December 2023) among women living with HIV aged ≥40 years from the WHO European region. Five dimensions of care were assessed: content of care, information, relationship with caregiver, organization of care, and patients' rights and privacy, in addition to management of non-HIV comorbidities and menopause.
Background: Effective antiretroviral therapy (ART) has improved the life expectancy of people with HIV (PWH). However, this population is now experiencing accelerated age-related comorbidities, contributed to by chronic immune activation and inflammation, with dysbiosis of the gut microbiome also implicated.
Method: We conducted a systematic literature search of PubMed, Embase, Scopus, Cochrane reviews and international conference abstracts for articles that examined for the following non-communicable diseases (NCDs); cardiovascular disease, cancer, frailty, metabolic, bone, renal and neurocognitive disease, in PWH aged >18 years.
Article Synopsis
- - The study aimed to determine how psychosocial factors contribute to differences in cognitive performance between individuals with and without HIV, involving 273 participants from Cape Town, South Africa.
- - Researchers conducted cognitive tests across seven areas and evaluated 12 psychosocial measures, discovering that individuals with HIV scored lower in nearly all psychosocial variables and experienced a significant reduction in cognitive performance compared to those without HIV.
- - Findings revealed that while some of the cognitive impairment linked to HIV could be explained by demographic and psychosocial factors, there remained a significant association indicating that these adjustments alone do not fully account for cognitive deficits.