Publications by authors named "C A Pistolese"
Article Synopsis
- Vacuum-assisted excision (VAE) is becoming a popular method for managing B3 breast lesions, but its long-term imaging effects are not well documented in existing literature.
- This case report discusses a challenging instance where the VAE site appeared as a mass, resembling breast cancer, which raises concerns about imaging interpretation.
- The authors aim to enhance understanding of the ultrasound and mammographic features of the area post-VAE to improve radiological knowledge and practices.
Radiological and pathological predictors of post-operative upstaging of breast ductal carcinoma in situ (DCIS) to invasive ductal carcinoma and lymph-nodes metastasis; a potential algorithm for node surgical de-escalation.
Surg Oncol
October 2024
Background/aim: Ductal carcinoma in situ is considered a local disease with no metastatic potential, thus sentinel lymph node biopsy (SLNB) may be deemed an overtreatment. SLNB should be reserved for patients with invasive cancer, even though the risk of upstaging rises to 25 %. We aimed to identify clinicopathological predictors of post-operative upstaging in invasive carcinoma.
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- - The study explored the effectiveness of contrast enhancement ultrasound (CEUS) as a non-invasive method for identifying sentinel lymph nodes (SLNs) in early breast cancer patients, comparing it to the traditional sentinel lymph node biopsy (SLNB) technique.
- - Conducted as part of a larger phase 3 study, the research involved patients undergoing surgery for early breast cancer, where CEUS helped locate and mark lymph nodes for later analysis, with a focus on identifying any cancerous cells present.
- - Results showed that CEUS successfully identified and marked lymph nodes in most patients, with a significant portion demonstrating pathological findings, indicating its potential as a safe alternative for assessing axillary disease burden in early breast cancer cases.
Traditional imaging techniques for breast cancer (BC) diagnosis and prediction, such as X-rays and magnetic resonance imaging (MRI), demonstrate varying sensitivity and specificity due to clinical and technological factors. Consequently, positron emission tomography (PET), capable of detecting abnormal metabolic activity, has emerged as a more effective tool, providing critical quantitative and qualitative tumor-related metabolic information. This study leverages a public clinical dataset of dynamic F-Fluorothymidine (FLT) PET scans from BC patients, extending conventional static radiomics methods to the time domain-termed as 'Dynomics'.
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- The study looked at how the COVID-19 pandemic changed how breast cancer patients reacted to treatment in different time periods: before, during, and after the pandemic.
- During the pandemic, more patients refused surgeries compared to before or after it.
- Now, it seems that the pandemic doesn't really impact patients' decisions about getting treatments anymore because of new safety measures.