Publications by authors named "C A Kaminski"
The integration of Machine Learning (ML) with super-resolution microscopy represents a transformative advancement in biomedical research. Recent advances in ML, particularly deep learning (DL), have significantly enhanced image processing tasks, such as denoising and reconstruction. This review explores the growing potential of automation in super-resolution microscopy, focusing on how DL can enable autonomous imaging tasks.
View Article and Find Full Text PDFThe Antarctic seabed harbors significant biodiversity, and almost 90% of oceanic environments are permanently below 5 °C (i.e., deep sea and polar regions).
View Article and Find Full Text PDFBackground: Whole blood (WB) resuscitation has been shown to provide mortality benefit. However, the impact of whole blood transfusions on the risk of venous thromboembolism (VTE) remains unclear. We sought to compare the VTE risk in patients resuscitated with WB vs component therapy (COMP).
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- During neurogenesis, an initially excessive number of neurons are formed in the nervous system, but many are later eliminated through a process called apoptosis, or programmed cell death.
- This elimination is influenced by targets of innervation, which produce neurotrophic factors that help maturing neurons survive and grow as they connect with these targets.
- Research in mice shows that while neurogenesis and apoptosis typically complete within the first few days after birth, both processes continue significantly longer, indicating neurogenesis may play a role in replacing neurons lost during synaptic refinement.
Membrane-less compartments and organelles are widely acknowledged for their role in regulating cellular processes, and there is an urgent need to harness their full potential as both structural and functional elements of synthetic cells. Despite rapid progress, synthetically recapitulating the nonequilibrium, spatially distributed responses of natural membrane-less organelles remains elusive. Here, we demonstrate that the activity of nucleic-acid cleaving enzymes can be localized within DNA-based membrane-less compartments by sequestering the respective DNA or RNA substrates.
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