Publications by authors named "C A Hakim"
Purpose: We observed that the tumor microenvironment (TME) in metastatic epithelial ovarian cancer (EOC) and in other solid tumors can reprogram normal neutrophils to acquire a complement-dependent suppressor phenotype characterized by inhibition of stimulated T cell activation. This study aims to evaluate whether serum markers of neutrophil activation and complement at diagnosis of EOC would be associated with clinical outcomes.
Experimental Design: We conducted a two-center prospective study of patients with newly diagnosed EOC (N = 188).
Background: Unfortunately, current beauty trends greatly advertised by social media are trespassing recognized cannons of beauty. Of particular interest are patients' expectations of soft tissue volume augmentation of the face, specifically of the lips.
Methods: An artificial intelligence picture of a White female face was generated.
Excessive cytosolic calcium accumulation contributes to muscle degeneration in Duchenne muscular dystrophy (DMD). Sarco/endoplasmic reticulum calcium ATPase (SERCA) is a sarcoplasmic reticulum (SR) calcium pump that actively transports calcium from the cytosol into the SR. We previously showed that adeno-associated virus (AAV)-mediated SERCA2a therapy reduced cytosolic calcium overload and improved muscle and heart function in the murine DMD model.
View Article and Find Full Text PDFBackground Digital breast tomosynthesis (DBT) is often inadequate for screening women with a personal history of breast cancer (PHBC). The ongoing prospective Tomosynthesis or Contrast-Enhanced Mammography, or TOCEM, trial includes three annual screenings with both DBT and contrast-enhanced mammography (CEM). Purpose To perform interim assessment of cancer yield, stage, and recall rate when CEM is added to DBT in women with PHBC.
View Article and Find Full Text PDFDetermination of Appropriate Umbilicus Position during Abdominoplasty in Male Patients.
Plast Reconstr Surg Glob Open
October 2023
Article Synopsis
- The study investigates the ideal position of the umbilicus (belly button) in male cosmetic abdominoplasty, focusing on its anthropometric measurements to improve surgical outcomes.
- Researchers found a strong correlation between umbilicus position relative to the anterior axillary fold and nipple positions, suggesting that these reference points are better for determining umbilicus placement than relying only on the abdominal crease.
- The results propose a new predictive equation (U-AX = 1.618 × N-N) for umbilicus repositioning that emphasizes the aesthetic unity of the chest and abdomen in male patients.