ANTIMALARIAL activities and alkaloids from Crinum jagus (Thomps) DANDY.

Ethnopharmacological Relevance: Locally, among the Yoruba speaking people of South Western, Nigeria, the bulb of Crinum jagus (CJ), known as "ogede odo" is used to treat malaria and as an anthelmintic among other uses.

Aims Of This Study: Study aimed at identifying the purified active fractions and constituents of this fraction in an antiplasmodial activity-guided process.

Materials And Methods: Antiplasmodial activity-guided fractionation of the bulb and leaf extracts of CJ was investigated against chloroquine-sensitive (NK 65) Plasmodium berghei using 4-day suppressive and prophylactic methods.

Neuroprotective flavonoids of the leaf of Antiaris africana Englea against cyanide toxicity.

Ethnopharmacological Relevance: Different parts of Antiaris africana Englea (Moraceae) are used traditionally for the treatment of various diseases, including epilepsy and other nervous system disorders.

Aims Of This Study: The current study was designed to evaluate the neuroprotective activity of flavonoids isolated from A. africana against potassium cyanide (KCN)-induced oxidative damage in brain homogenate.

Bioactivity-directed evaluation of fruit of Kigelia africana (Lam.) benth. Used in treatment of malaria in Iwo, Nigeria.

Ethnopharmacological Relevance: The ancient people of Iwo communities consisting of Ile-Ogbo, Olupona, Iwo and Ogbagba continue to engage in the traditional use of medicinal plants for the treatment and management of common diseases especially malaria.

Aims Of This Study: This study conducted an ethnomedicinal survey of plants used to treat malaria and feverish conditions by the people of Iwo, Nigeria. It also evaluated the antiplasmodial activity of the morphological parts of Kigelia africana (Lam.

Involvement of the Benzodiazepine Site in the Anticonvulsant Activity of Tapinanthus globiferus against Pentylenetetrazole-induced Seizures in Mice.

is often referred to as an all-purpose herb for the treatment of stroke and epilepsy. The present study investigates the anticonvulsant effect of methanolic leaf extract, active fractions, and lupeol (isolate) of in mice as well as the underlying mechanisms. Following phytochemical studies of , preliminary assays were performed to evaluate MLE-induced toxic effect and behavioral changes.

Memory enhancing, anticholinesterase and antimicrobial activities of β-phenylnitroethane and essential oil of Dennettia tripetala Baker f.

Ethnopharmacological Relevance: Dennettia tripetala Baker f. belonging to the family Annonaceae is an important food and medicinal plant used in some local communities in Southwest Nigeria.

Aims Of The Study: The study aims at determining the chemical composition of the essential oil of different morphological parts of D.