Publications by authors named "C A Dow"
Background: The relationship between maternal obesity and childhood cognitive development remains unclear. Prior studies did not adjust for important confounders, and preterm infants are a developmentally distinct group that remains scarcely examined.
Objectives: To determine whether maternal prepregnancy body mass index (BMI) is associated with offspring intelligence quotient (IQ) up to 5 years and whether this relationship varies with gestational age.
Cognitive impairment following surgery is a significant complication, affecting multiple neurocognitive domains. The term "perioperative neurocognitive disorders" (PND) is recommended to encompass this entity. Individuals who develop PND are typically older and have increases in serum and brain pro-inflammatory cytokines notwithstanding the type of surgery undergone.
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- A study investigated how the antioxidant capacity and inflammation potential of maternal diets during the last three months of pregnancy could influence the risk of allergic and respiratory diseases in children.
- Researchers analyzed data from 9,679 mother-child pairs, measuring the dietary antioxidant capacity and inflammatory potential using various indices.
- Results indicated that a diet high in antioxidants was linked to a lower risk of 'early wheeze without asthma,' while a pro-inflammatory diet correlated with a higher risk of 'asthma only,' suggesting maternal diet impacts children's respiratory health to some extent.
Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections that, over millions of years, became integrated into the human genome. While normally inactive, environmental stimuli such as infections have contributed to the transcriptional reactivation of HERV-promoting pathological conditions, including the development of autoimmunity, neurodegenerative disease and cancer. What infections trigger HERV activation? subspecies (MAP) is a pluripotent driver of human disease.
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- The study investigates how maternal diet during pregnancy affects exposure to toxic trace elements like arsenic, mercury, and lead.
- It found that women with healthier dietary patterns had higher levels of arsenic and mercury in their bodies, while lead levels in cord blood were less directly linked to diet.
- Interestingly, a Western dietary pattern was connected to lower mercury levels, suggesting that not all "healthy" foods are equal when it comes to toxic exposure during pregnancy.