Publications by authors named "C A Denier"
Article Synopsis
- Thrombolysis and endovascular thrombectomy (EVT) are standard stroke treatments, and this study investigates their effectiveness specifically in nonagenarians (patients aged 90 and older), hypothesizing that their prognosis may be worse than that of younger patients.
- The study analyzed outcomes of 96 nonagenarians treated with these therapies, finding that they had more pre-existing health conditions and lower independence before the stroke compared to patients aged 80-89.
- Results indicated that while treatment timelines and successful reperfusion rates were similar, nonagenarians had significantly poorer functional recovery at 3 months (14.3% vs. 34.0%) and a much higher mortality rate (60.2% compared to 16
Article Synopsis
- The study examined cerebral venous thrombosis (CVT) characteristics in elderly patients (65 years and older) across nine hospitals in the Paris-Ile-de-France region from 2011 to 2021.
- Researchers found that the annual incidence of CVT in this demographic was lower compared to the national average, with headaches and focal deficits being the most common initial symptoms.
- The results indicated that elderly patients had a distinct clinical profile, with higher rates of underlying conditions like cancer and a worse prognosis than younger adults, highlighting the need for specialized care in this age group.
Background: Timely revascularization in acute arterial ischemic stroke (AIS) is paramount for optimal outcomes. However, factors causing treatment delays in pediatric AIS remain understudied. We investigated determinants affecting the time from symptom onset or last-known-well to the start of recanalization treatment in pediatric AIS.
View Article and Find Full Text PDFBackground: The use of thrombectomy in patients with acute stroke and a large infarct of unrestricted size has not been well studied.
Methods: We assigned, in a 1:1 ratio, patients with proximal cerebral vessel occlusion in the anterior circulation and a large infarct (as defined by an Alberta Stroke Program Early Computed Tomographic Score of ≤5; values range from 0 to 10) detected on magnetic resonance imaging or computed tomography within 6.5 hours after symptom onset to undergo endovascular thrombectomy and receive medical care (thrombectomy group) or to receive medical care alone (control group).