Publications by authors named "C A D'Este"

Background: The Quality in Acute Stroke Care (QASC) Trial demonstrated that assistance to implement protocols to manage Fever, hyperglycaemia (Sugar) and Swallowing (FeSS) post-stroke reduced death and disability. In 2017, a 'Strong Recommendation' for use of FeSS Protocols was included in the Australian Clinical Guidelines for Stroke Management. We aimed to: i) compare adherence to FeSS Protocols pre- and post-guideline inclusion; ii) determine if adherence varied with prior participation in a treatment arm of a FeSS Intervention study, or receiving treatment in a stroke unit; and compare findings with our previous studies.

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  • - The study evaluated the impact of nurse-led implementation of protocols to manage fever, hyperglycemia, and swallowing in German stroke units, showing significant improvements in adherence to these protocols after training and support from an Australian team.
  • - Results indicated a notable increase in overall adherence from 20% to 28%, with specific improvements in managing hyperglycemia (from 43% to 55%) and swallowing (from 52% to 61%), though fever protocol adherence showed little change.
  • - Additional findings revealed increased timely administration of anti-pyretics and insulin, as well as improved screening for swallowing within 24 hours of admission, highlighting the effectiveness of the implemented support strategies.
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  • * A cluster randomised controlled trial will be conducted in Sydney to test a new integrated approach for secondary fracture prevention in primary care settings, which includes alerts to doctors and management guidelines for osteoporotic fractures.
  • * The primary goal of the trial is to measure how many patients get bone density scans or prescriptions for osteoporosis treatment within three months of an initial fracture diagnosis, while also tracking additional outcomes related to osteoporosis management.
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  • A study investigated the impact of PFAS contamination from aqueous film forming foams (AFFF) on child development in three Australian towns: Katherine, Oakey, and Williamtown.
  • Findings indicated mixed results, with lower risk of developmental vulnerability in Katherine but higher risks in Oakey, specifically for communication skills and physical health.
  • The overall conclusion suggested insufficient evidence to link increased developmental vulnerabilities to living in PFAS-affected areas.
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Background: Anemia poses a significant public health problem, affecting 1.6 billion people and contributing to the loss of 68.4 million disability-adjusted life years.

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