Vaginal screening for group B streptococcus using PCR in pregnant women with unknown colonization status: Impact on newborn monitoring for early-onset sepsis.

Background: Early-onset neonatal sepsis represents a diagnostic challenge, as it is a cause of neonatal mortality and morbidity. Guidelines for the prevention of group B streptococcus (GBS) infection recommend that all pregnant women must be screened for GBS carriage at the end of pregnancy, with intrapartum antibiotic prophylaxis being provided for GBS carriers. If vaginal culture is not available, GBS polymerase chain reaction (GBS-PCR) is an alternative option for this type of screening.

Clinical audit of quality of care among patients with viral hepatitis in primary care in a low endemic region.

Background: The current hepatitis B (HBV) and hepatitis C virus (HCV) screening practices may fail to detect many infected patients who could benefit from new therapeutic agents to limit progression to cirrhosis and hepatocellular carcinoma.

Objectives: This study assessed the test positivity rate and cascade of care of viral hepatitis patients in primary care in a low endemic region as well as the testing policy of abnormal alanine aminotransferase (ALT) level.

Methods: This is a retrospective clinical audit among primary health care practices in Flanders, Belgium, assessing patients with an active medical file between 2019 and 2021.

Antifungal activity of extracts from species against .

causes destructive ear rot diseases in maize and wheat. New antifungals are essential to combat this pathogen, and aerial parts of species (Acanthaceae) are a potential source. We investigated the antifungal activity of extracts from stems and leaves of five species native to Northwest Argentina.

Trypanocidal and Anti-Inflammatory Effects of Three -Kaurane Diterpenoids from var. (Asteraceae).

Chagas disease, caused by the protozoan , affects 6-7 million people worldwide. The dichloromethane extract obtained from the aerial parts of var showed trypanocidal activity in vitro. The fractionation of the dewaxed organic extract via column chromatography led to the isolation of three diterpenoids: -9α,11α-dihydroxy-15-oxo-kaur-16-en-19-oic acid or adenostemmoic acid B, (16)--11α-hydroxy-15-oxokauran-19-oic acid and -11α-hydroxy-15-oxo-kaur-16-en-19-oic acid.