Image-guided tumour ablation is a minimally invasive treatment for early stage hepatocellular carcinoma (HCC). Our study reviews the complications and long term outcomes in patients treated at a tertiary referral centre. Retrospective study.
View Article and Find Full Text PDFAlzheimer's Disease and Alzheimer's Disease-related dementias (AD/ADRD) pose major global healthcare challenges, with diabetes mellitus (DM) being a key risk factor. Both AD and DM-related ADRD are characterized by reduced cerebral blood flow, although the exact mechanisms remain unclear. We previously identified compromised cerebral hemodynamics as early signs in TgF344-AD and type 2 DM-ADRD (T2DN) rat models.
View Article and Find Full Text PDFThe purpose of this study was to examine the differences in braking and propulsion force-time characteristics and barbell velocity between traditional (TRAD) and accentuated eccentric loaded (AEL) back squats using various load combinations. Sixteen resistance-trained men participated in four separate testing sessions which included a one repetition maximum (1RM) back squat during the first session and three squat testing sessions. During the squat testing sessions, participants either performed sets of three repetitions of TRAD back squats each with 50, 60, 70, and 80% 1RM or performed the same loads with the addition of weight releasers that increased the total eccentric weight of the first repetition of each set to either 100 (AEL-MAX) or 110% 1RM (AEL-SUPRA).
View Article and Find Full Text PDFMicromachines (Basel)
December 2023
Using devices with microfluidic channels can allow for precise control over liquids flowing through them. Merging flows of immiscible liquids can create emulsions with highly monodispersed microdroplets within a carrier liquid, which are ideal for miniaturised reaction vessels which can be generated with a high throughput of tens of thousands of droplets per second. Control of the size and composition of these droplets is generally performed by controlling the pumping system pushing the liquids into the device; however, this is an indirect manipulation and inadequate if absolute precision is required in the size or composition of the droplets.
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