Assessment and management of frailty in individuals living with dementia: expert recommendations for clinical practice.

Frailty complicates the care of individuals with dementia, increasing their vulnerability to adverse outcomes. This Personal View presents expert recommendations for managing frailty in individuals with dementia, aimed at health-care providers, particularly those in primary care. We conducted a rapid literature review followed by a consensus process involving 18 international experts on dementia and frailty.

Regenerative characteristics of the immortal jellyfish, Turritopsis dohrnii, and their potential implications for human aging.

The jellyfish Turritopsis dohrnii (T. Nutricala) is a cnidarian of the Oceaniidae family that lives in the Mediterranean Sea. It is known as the immortal jellyfish since, through a process of cell development called transdifferentiation, it manages to return to a polyp state.

Cognitive Frailty and Aging: Clinical Characteristics, Pathophysiological Mechanisms, and Potential Prevention Strategies.

Frailty has been conceptualized not only as a physical disease, but also as a multidomain entity that encompasses a multimorbid status, disability, cognitive impairment, psychosocial risk factors, and even geriatric syndromes. In addition to physical ailments and depending on the diagnostic model. Standardized neuropsychological tests can identify cognitive deficiencies along with mild cognitive impairment, a pre-dementia stage characterized by memory and/or other cognitive domain impairments with relatively preserved instrumental activities of daily living.

[The functional continuum and hospital-associated functional decline in an Acute Geriatric Unit].

Background: Older adults are particularly vulnerable to experiencing hospital-associated functional decline; a multifaceted phenomenon linked to poorer outcomes and increased healthcare costs. Given that functionality serves as a crucial indicator of health in the elderly, various scales have been developed to gauge the continuum of functional ability, potentially serving as prognostic tools to inform tailored interventions.

Objectives: The aim of this study is to determine the prevalence of hospital-associated functional decline in an acute geriatric unit and examine its correlation with the functional continuum through a descriptive analysis of the patient population and exploration of associated factors.