Publications by authors named "C A Bona"
: In pituitary adenomas, examinations of surgical specimens have shown that dural invasion occurs in 42-85% of cases. No studies about dura mater invasion have been conducted specifically in acromegaly patients. The aim of the present study was to evaluate the relationship between histologically dural invasion and the main features of GH-secreting adenomas.
View Article and Find Full Text PDFEffect of Cabergoline on weight and glucose metabolism in patients with acromegaly.
J Endocrinol Invest
December 2024
Purpose: Cabergoline (CAB) has shown to have benefic effects on the metabolism in different clinical settings but its metabolic role in acromegaly disease has not been studied yet. Aim of our study was to evaluate the impact of CAB on glucose metabolism and weight in patients with acromegaly.
Methods: All patients with acromegaly undergoing continuous treatment with CAB for at least 6 months were retrospectively screened.
Purpose: Prolactin (PRL)-secreting tumours are associated with infertility and can be reverted by dopamine agonist (DA) therapy. The suspension of DA is recommended once pregnancy is established, as all DAs cross the placenta. The aim of the study was to evaluate the rate of maternal-foetal complications in women treated with cabergoline (CAB) or bromocriptine (BRM) for prolactinoma during gestation and the effect of pregnancy on prolactinoma progression.
View Article and Find Full Text PDFArticle Synopsis
- Brugada syndrome (BrS) is a genetic disorder that can lead to dangerous heart rhythms and sudden death in people with normal heart structures, with hypothyroidism being a potential triggering factor.
- A 33-year-old man with severe hypothyroidism exhibited a Brugada type 1 ECG pattern, and the relationship between severe thyroid dysfunction and ECG alterations is still not fully understood.
- Treatment with levothyroxine, even at low doses, led to a quick improvement in the patient's ECG readings, suggesting that hypothyroidism may contribute to Brugada syndrome symptoms.
Influence of Cigarette Smoking Habit on Clozapine-to-Norclozapine Ratio in Male Patients.
J Res Pharm Pract
November 2023
Objective: This study aimed to evaluate the influence of cigarette smoking habit on the clozapine (CLZ)-to-norclozapine (norCLZ) ratio in male patients.
Methods: The sample consisted of plasma concentration of CLZ and norCLZ data set. The mean values of CLZ, norCLZ, and CLZ-to-norCLZ, between male patients who smoke versus nonsmokers were compared.