Publications by authors named "C A Blum"
Article Synopsis
- Veno-venous extracorporeal membrane oxygenation (VV ECMO) is crucial for treating severe respiratory distress, but it often leads to complications like hemolysis and bleeding, which can increase mortality rates.
- This study analyzed data from 580 VV ECMO patients and utilized computational modeling to assess how pump operating conditions affect hemolysis, revealing that lower pump pressures and circuit resistance minimize blood trauma.
- The findings suggest that maintaining low circuit resistance, through using efficient oxygenators and tubing, is vital for reducing adverse effects related to ECMO support.
Article Synopsis
- This paper talks about "ant colony optimization," which is a smart way to solve tough problems, inspired by how ants find the best paths.
- It looks at how this method has been developed over time instead of just its uses.
- The main part of the paper also shows interesting trends about where the research is coming from and how ideas about it have changed over the years, using graphs and numbers.
Objectives: Medical cannabis (MC) has been found effective in treating multiple symptoms commonly experienced by older adults; however, residents in long-term care (LTC) often lack access to MC products. This study seeks to identify patterns and barriers to recommending MC to patients and to explore the knowledge and attitudes toward MC use among patients and providers.
Methods: The quantitative portion of this study employed a survey to assess the knowledge of, attitudes toward, and barriers to MC among 126 providers in Florida LTC.
Background: The anterior-based muscle-sparing (ABMS) approach, using the intramuscular interval between the tensor fascia lata and gluteus medius, is an increasingly popular total hip arthroplasty (THA) approach. Its incidence of lateral femoral cutaneous nerve (LFCN) numbness has not been defined. The incidence of LFCN symptoms in direct anterior THA ranges from 7%-32% at 1-year follow-up.
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- Decitabine (5-aza-dC) is a nucleoside analogue used for treating certain blood cancers, but its effectiveness can vary and relapses are common.
- Research using CRISPR/Cas9 screens identified that the loss of the enzyme DCTD makes cancer cells resistant to decitabine by reducing the production of 5-aza-dUMP, which is toxic to cells.
- The study revealed that the protein TOPORS helps repair decitabine-induced DNA damage and may be targeted for new biomarkers to predict how patients respond to decitabine treatment.