Predictive Accuracy of a Perioperative Laboratory Test-Based Prediction Model for Moderate to Severe Acute Kidney Injury After Cardiac Surgery.

Importance: Effective treatment of acute kidney injury (AKI) is predicated on timely diagnosis; however, the lag in the increase in serum creatinine levels after kidney injury may delay therapy initiation.

Objective: To determine the derivation and validation of predictive models for AKI after cardiac surgery.

Design, Setting, And Participants: Multivariable prediction models were derived based on a retrospective observational cohort of adult patients undergoing cardiac surgery between January 2000 and December 2019 from a US academic medical center (n = 58 526) and subsequently validated on an external cohort from 3 US community hospitals (n = 4734).

Biochemically diagnosed hypothyroidism and postoperative complications after cardiac surgery: a retrospective cohort analysis.

Purpose: To determine whether hypothyroidism is associated with cardiovascular complications and surgical wound infections after cardiac surgery.

Methods: Patients were categorized as: (1) hypothyroid [patients with increased TSH concentrations (≧ 5.5 mIU/L) within 6 months prior to surgery]; (2) corrected hypothyroid [diagnosis of hypothyroidism any time before surgery or on preoperative thyroid supplementation and normal TSH concentration (0.

Lack of Association between Preoperative Statin Use and Respiratory and Neurologic Complications after Cardiac Surgery.

Background: Statins may reduce the risk of pulmonary and neurologic complications after cardiac surgery.

Methods: The authors acquired data for adults who had coronary artery bypass graft, valve surgery, or combined procedures. The authors matched patients who took statins preoperatively to patients who did not.

The association between body mass index and outcome after coronary artery bypass grafting operations.

Objectives: This investigation was undertaken to analyse the association between body mass index (BMI) and morbidity after coronary artery bypass graft (CABG) operations.

Methods: The setting was a cardiovascular intensive care unit (ICU) of a tertiary medical referral centre. This was a retrospective review; patients were classified according to their BMI into five groups: underweight <18.

Preoperative brain natriuretic peptide and atrial arrhythmias after coronary artery bypass graft surgery.

Objective: To assess the association of preoperative brain natriuretic peptide with atrial arrhythmias and length of stay after cardiac surgery.

Design: A retrospective data analysis.

Setting: All data were collected from patients who underwent cardiac surgery at a single institution, an academic hospital, between 2005 and 2010.