Literature-based prediction of novel drug indications considering relationships between entities.

There have been many attempts to identify and develop new uses for existing drugs, which is known as drug repositioning. Among these efforts, text mining is an effective means of discovering novel knowledge from a large amount of literature data. We identify a gene regulation by a drug and a phenotype based on the biomedical literature.

Development of Child-Teen Obesity Treatment Service Platform.

Objectives: This study aimed to develop an effective and efficient obesity treatment and management service platform for obese children/teenagers.

Methods: The integrated smart platform was planned and established through cooperation with service providers such as hospitals and public health centers, obese children/teenagers who constitute the service's user base, and IT development and policy institutions and companies focusing on child-teen obesity management and treatment.

Results: Based on guidelines on intervention strategies to manage child-teen obesity, we developed two patient/parent mobile applications, one web-monitoring service for medical staff, one mobile application for food-craving endurance, and one mobile application for medical examinations.

A study on the effect of self bedside exercise program on resilience and activities of daily living for patients with hemiplegia.

The purpose of this study was to design a repeatable universal rehabilitation program in which patients with hemiplegia can participate voluntarily, complementing physical and occupational therapies to increase voluntary exercise practice rate. Also, this study attempted to identify the relationship between psychological resilience due to the implementation of self-bedside exercise and functional recovery of activity of daily living (ADL). 12 patients with hemiplegia voluntarily participated in 8 weeks of self-bedside exercise 5 times a day and more than 5 days a week.

The order of priority in standardization of ubiquitous home healthcare technology.

This research establishes the priority based on the 4 different evaluation criteria and identifies 24 home healthcare technologies with Analytic Hierarchy Process method through the surveys to the expert groups and the experiments of group interviewing in order to determine the priority of home healthcare technology standardization for more activated service.

An architectural framework for an adverse drug event surveillance system.

Much effort has focused on detecting as many adverse drug events (ADEs) as possible, as soon possible. An ADE surveillance system (ADESS) is a computerized surveillance system that detects ADEs automatically, by analyzing medication orders, laboratory results, and medical records. We propose a new ADESS architectural framework using the object-oriented component-based development (OOCBD) methodology to extract and analyze ADEs automatically, with a minimal server-side workload.