Differential effects of white matter hyperintensity on geriatric depressive symptoms according to APOE-ε4 status.

Background: We aimed to examine differential effects of WMH on progression of depressive symptoms according to APOE ε4 status in the elderly.

Methods: We obtained data from elderly Korean subjects (n=707) aged 60 years or older at baseline from the CREDOS study from November 2005 to July 2014. A linear mixed model stratified according to APOE genotype (APOE ε4 carrier vs.

Carbon beam extraction with 14.5 GHz electron cyclotron resonance ion source at Korea Atomic Energy Research Institute.

A 14.5 GHz Electron Cyclotron Resonance ion source (ECRIS) has been made to produce C(4+) beam for using a carbon therapy facility and recently tested at KAERI. Highly charged carbon ions have been successfully extracted.

Fabrication of an optimized hexapole magnet for a 14.5 GHz electron cyclotron resonance ion source.

A hexapole magnet for a 14.5 GHz electron cyclotron resonance (ECR) ion source, where the maximum radial field on the wall of the plasma chamber is higher than 1.1 T, has been designed and fabricated.

Increased plasma levels of heat shock protein 70 in patients with vascular mild cognitive impairment.

Heat shock proteins (Hsps) have been regarded as cytoprotectants that protect brain cells from damage encountered following cerebral ischemia or during the progression of neurodegenerative diseases. In this study, we assessed the plasma Hsp70 and Hsp27 levels in not cognitively impaired (NCI) subjects and in patients with mild cognitive impairment (MCI), vascular mild cognitive impairment (VMCI), and probable Alzheimer's disease (AD). Comparison of the plasma Hsp70 and Hsp27 levels of the 4 groups revealed that only the plasma Hsp70 level of VMCI patients (14.

Long pulse beam extraction with a prototype ion source for the KSTAR neutral beam system.

Long pulse operational characteristics of the high current ion source for the KSTAR neutral beam system are described. The beam pulse length of 300 s was successfully operated at a beam power of 1.6 MW with a beam energy of 70 keV.

Study on an azimuthal line cusp ion source for the KSTAR neutral beam injector.

In this study it is found that the cusp magnetic field configuration of an anode bucket influences the primary electron behavior. An electron orbit code (ELEORBIT code) showed that an azimuthal line cusp (cusp lines run azimuthally with respect to the beam extraction direction) provides a longer primary electron confinement time than an axial line cusp configuration. Experimentally higher plasma densities were obtained under the same arc power when the azimuthal cusp chamber was used.

Influence of the serotonin transporter promoter gene polymorphism on susceptibility to posttraumatic stress disorder.

Posttraumatic stress disorder (PTSD) is a prevalent anxiety disorder marked by behavioral, physiologic, and hormonal alterations. The etiology of PTSD is unknown, although exposure to a traumatic event constitutes a necessary, but not sufficient, factor. Serotonergic dysfunction has been implicated in PTSD.

Expression of mRNA transcripts of the Na+/H+ and Cl-/HCO3- exchanger isoforms in human nasal mucosa.

Electrolyte transport by nasal epithelia has been suggested to be important for controlling the quantity and composition of the nasal fluid and may play an important role in the development of nasal polyps. One of a number of mechanisms involving translocation of Na+ and Cl- across cell membranes includes electroneutral processes, such as Na+/H+ exchange (NHE) and Cl-/HCO3- exchange (AE). The present study evaluated the presence of mRNAs for various members of the human NHE and AE gene families in human inferior turbinate mucosa and nasal polyp using reverse transcriptase polymerase chain reaction and in situ hybridization.