Publications by authors named "Byron Alex"

Introduction: Acquired rifamycin resistance (ARR) in tuberculosis (TB) has been associated with HIV infection and can necessitate complicated TB treatment regimens, particularly in people living with HIV (PLWH). This work examines clinical characteristics and treatment outcomes of PLWH who developed ARR from 2001 to 2023 in New York City (NYC) to inform best practices for treating these patients.

Methods: PLWH who developed ARR 2001-2023 were identified from the NYC TB registry.

View Article and Find Full Text PDF

Mercury is a toxic metal that can be measured in human blood and urine. Population-based biomonitoring from 2004 guided New York City (NYC) Department of Health and Mental Hygiene (DOHMH) efforts to reduce exposures by educating the public about risks and benefits of fish consumption-a predominant source of exposure in the general population-and removing mercury-containing skin-lightening creams and other consumer products from the marketplace. We describe changes in exposures over the past decade in relation to these local public health actions and in the context of national changes by comparing mercury concentrations measured in blood (1201 specimens) and urine (1408 specimens) from the NYC Health and Nutrition Examination Survey (NYC HANES) 2013-2014 with measurements from NYC HANES 2004 and National Health and Nutrition Examination Surveys (NHANES) 2003-2004 and 2013-2014.

View Article and Find Full Text PDF

Ketamine is an emerging therapy for pediatric refractory status epilepticus. The circumstances of its use, however, are understudied. The authors described pediatric refractory status epilepticus treated with ketamine from 2010 to 2014 at 45 centers using the Pediatric Hospital Inpatient System database.

View Article and Find Full Text PDF

The period immediately after release from prison or jail carries increased mortality risk. This study sought to better understand postrelease death by matching electronic health records from those incarcerated in New York City jails between 2011 and 2012 with vital statistics records. The in-jail and 6-week postrelease mortality rates were estimated to be 1.

View Article and Find Full Text PDF

Objective: To define predictors of the deformity stabilisation and improvement in men with untreated Peyronie's disease (PD).

Patients And Methods: The study population consisted of patients with PD-associated uniplanar curvature, who opted for no treatment and were followed for at least 12 months. All patients had deformity assessment (DA) performed on initial presentation and at follow-up.

View Article and Find Full Text PDF

Introduction: Peyronie's disease (PD) is commonly seen in middle-aged men, and little is known about this condition in teenagers.

Aim: To investigate the characteristics of PD in teenagers.

Methods: The findings were compared between patients with the disease who were teenagers with those over 40 years of age.

View Article and Find Full Text PDF

Objective: • To assess factors that predict penile curvature responses to intralesional verapamil (ILV) injection therapy for men with Peyronie's disease (PD).

Patients And Methods: • Men with PD for <1 year were assessed at baseline and after 3 months of bi-monthly ILV-injection therapy. Curvature was assessed at the time of maximum penile rigidity.

View Article and Find Full Text PDF

Introduction: Plaque incision and grafting (PIG) surgery for Peyronie's disease (PD) is a recognized management strategy. One of the recognized complications of PIG surgery is the development of postoperative erectile dysfunction (ED).

Aim: To determine the incidence of ED after PIG surgery and attempt to define predictors of ED development.

View Article and Find Full Text PDF

The impact of social and economic determinants of health status and the existence of racial and ethnic health care access disparities have been well-documented. This paper describes a model, the Health Care Access Barriers Model (HCAB), which provides a taxonomy and practical framework for the classification, analysis and reporting of those modifiable health care access barriers that are associated with health care disparities. The model describes three categories of modifiable health care access barriers: financial, structural, and cognitive.

View Article and Find Full Text PDF

Introduction: Many men with Peyronie's disease (PD) delay presentation to a urologist. The reasons for this are unclear.

Aim: To define the differences in men who present early compared to those presenting in a delayed fashion and to determine predictors of delayed presentation.

View Article and Find Full Text PDF

Surfactant lines the alveolar surface and prevents alveolar collapse. Derangements of surfactant cause respiratory failure and interstitial lung diseases. The collectins, surfactant proteins A and D, are also important in innate host defense.

View Article and Find Full Text PDF