Functionalization of Multi-Walled Carbon Nanotubes Changes Their Antibiofilm and Probiofilm Effects on Environmental Bacteria.

Releasing multi-walled carbon nanotubes (MWCNTs) into ecosystems affects the biofilm formation and metabolic activity of bacteria in aquatic and soil environments. Pristine (pMWCNTs), oleophilic (oMWCNTs), hydrophilic (hMWCNTs), and carboxylated (cMWCNTs) carbon nanotubes were used to investigate their effects on bacterial biofilm. A pronounced probiofilm effect of modified MWCNTs was observed on the Gram-negative bacteria of C2, 11 h, and 2.

[Use of natural platelet autoplasma and its thermally processed modifications for correction of age changes of skin.].

The article describes the results of a comparative prospective study of the results of correcting age-related changes in the skin of the face and neck in 72 patients using native platelet auto plasma and a new method for obtaining its thermally processed modifications based on the denaturation of protein plasma fractions when heated in a thermostat to different temperatures. (Patent No. 2629527/August 29, 2017.

[Quantitative evaluation of the quality of external beam radiotherapy planning of patients with cervical cancer].

The evaluation of the quality of external radiotherapy plans in patients with cervical cancer was performed. There was analyzed homogeneity index in the target volume (PTV), conformity index and others for 53 patients. Homogeneity and conformity indexes within the tolerances were achievable in the clinic with the implementation of technology 3D CRT, IMRT and Rapid Arc.

[Possibilities of stereotactic radiotherapy in the palliative treatment of patients with pancreatic cancer].

Morbidity and mortality from pancreatic cancer is steadily increasing. Resectable cases are not more than 20%. Conventional schemes of chemoradiation and radiation therapy are durable over the time, have toxicity and low treatment outcomes.

[The role of stereotactic radiotherapy in the treatment of patients with liver metastases].

Application of modern linear electron accelerators, equipped with precise navigation systems, maximum conformal dose delivery as well as imaging of irradiated focus significantly increased possibilities of escalating of doses of ionizing radiation in a selected volume with the necessary protection of the surrounding critical structures. These technological solutions and modern ideas about possibilities of remote beam radiation therapy resulted in a significant increase of the role of radiation therapy and, in particular, stereotactic radiotherapy in the treatment of patients with liver metastases. This technique allows creating locally in metastatic tumor site a high dose of ionizing radiation causing by that the destruction of the tumor.

[Complex treatment of breast cancer patients with brain metastases].

Brain metastases in breast cancer develop for 24-32 months after the detection of the primary tumor. The study included patients with brain metastases who were divided into three groups: the first group--with early chemoradiotherapy (CRT) without induction chemotherapy (IC) by capecitabine; the second group--with delayed CRT with 4 or 8 courses of IC by capecitabine; the third group (a historical control) who received only whole brain radiation therapy. The median time to progression of intracranial metastases was 15.