Publications by authors named "Byeongmin Shin"
Article Synopsis
- Atopic dermatitis (AD) involves a Th2 inflammatory response damaging the skin, and there's a strong link between this condition and a specific strain of bacteria, A2-165, known for producing butyrate.
- Researchers have determined the 3D structure of an important enzyme, 3-hydroxybutyryl-CoA dehydrogenase (A2HBD), using advanced X-ray techniques, revealing its interactions with key molecules like acetoacetyl-CoA and NAD.
- The study highlights significant conformational changes in A2HBD when substrates bind, particularly noting how specific residues contribute to substrate recognition and the enzyme's overall catalytic activity.
The exosome multiprotein complex plays a critical role in RNA processing and degradation. This system governs the regulation of mRNA quality, degradation in the cytoplasm, the processing of short noncoding RNA, and the breakdown of RNA fragments. We determined two crystal structures of exosome components from (): one with a resolution of 2.
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