Publications by authors named "Byeongho Jung"

Introduction: The management of benign bone lesions is controversial as it is dependent on a multitude of factors such as age, anatomic location, comorbidities, lesion metabolic activity, surgeon preferences, and goals of care, among others. Thus far, many studies have attempted to report on these lesions; however, most are heterogeneous compilations of benign and malignant lesions with nearly all failing to report patient treatment and none of which have originated from a suburban area of the United States. The goal of this study was to establish a modern database dedicated solely to benign bone tumors to reflect current diagnosis and treatment trends in suburban New York.

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Article Synopsis
  • Chronic lymphocytic leukemia (CLL) is characterized by the growth of a specific type of B cells and relies on interactions with T cells, particularly increasing levels of IL-17A+ and IL-17F+ CD4+ T (Th17) cells, which can lead to better patient outcomes.
  • CLL Th17 cells have higher miR155 expression levels compared to normal Th17 cells, while naive CD4+ T (Tn) cells show similar baseline levels of miR155.
  • CLL Bact cells influence miR155 levels in Tn cells, thereby promoting the production of IL-17A+ and IL-17F+ T cells; this correlation is linked to patient outcomes
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Background: Hip instability following total hip arthroplasty (THA) can be a major cause of revision surgery. Physiological patient position impacts acetabular anteversion and abduction, and influences the functional component positioning. Osteoarthritis of the spine leads to abnormal spinopelvic biomechanics and motion, but there is no consensus on the degree of component variability for THAs performed by anterior approach.

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Cancer pathogenesis involves the interplay of tumor- and microenvironment-derived stimuli. Here we focused on the influence of an immunomodulatory cell type, myeloid-derived suppressor cells (MDSCs), and their lineage-related subtypes on autologous T lymphocytes. Although MDSCs as a group correlated with an immunosuppressive Th repertoire and worse clinical course, MDSC subtypes (polymorphonuclear, PMN-MDSC, and monocytic, M-MDSCs) were often functionally discordant.

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