S-AMLODIPINE AS A MODERN EFFECTIVE ANTIHYPERTENSIVE AND AN ANTIANGINAL AGENT.

Objective: The aim: Study of the clinical and hemodynamic effects of S-amlodipine in patients with arterial hypertension associated with coronary artery disease, in individuals with preserved LV systolic function.

Patients And Methods: Materials and methods: The study includes 51 patients with arterial hypertension associated with coronary artery disease, who were treated with S-amlodipine.

Results: Results: This study shows the high clinical effectiveness of the use of S-amlodipine in patients with arterial hypertension associated with coronary artery disease.

PREDICTING PROGRESSION TYPE 2 DIABETES MELLITUS: A 3-YEAR FOLLOW-UP STUDY EXAMINING RISK FACTORS FOR TYPE 2 DIABETES IN PATIENTS WITH PREDIABETES.

Objective: Aim: To study the risk factors in patients with prediabetes that can lead to the progression of impaired glucose tolerance in the form of type 2 diabetes mellitus.

Patients And Methods: Materials and methods: The selection of patients for this study was carried out on an outpatient basis at the Department of Therapy and Family Medicine, Uzhhorod National University. Patients with prediabetes were identified based on the American Diabetes Association criteria.

[The value of transendoscopy thermometry of gastric mucosa in the evaluation of blood flow in patients with osteoarthrosis and atherosclerosis by duplex ultrasound of extracranial brachiocephalic arteries].

The pathogenesis of gastric mucosa lesions in elderly and senile people has many factors. It's based on contradiction between protective factors (mucus secretion, prostaglandins, bicarbonate, microcirculation, regeneration, etc.) and aggression factors (hydrochloric acid, pepsin, bile acids, pancreatic enzymes, bacteria).

[Clinical and hemodynamic effects of diltiazem in patients with arterial hypertension associated with ischemic heart disease].

In this research was light up the high clinical effectivity of the diltiazem in patient with arterial hypertension, connected with ischemic heart disease. Monotherapy with the diltiazem had not influenced on the contractive quality of the left ventricle. Therapy with the diltiazem considerably improve the diastolic function of the left ventricle and approach it to the standard.

[Clinical hemodynamic effects of amlodipine in patients with hypertension associated with angina pectoris].

This research highlights high clinical affectivity of Amlodipine in patients with essential hypertension complicated by ishemic heart disease. Monotherapy with Amlodipine doesn't deteriorate contractive quality of the left ventricle. Therapy with Amlodipine considerably improves the diastolic function of the left ventricle and adjusts it.

[Results of long-term administration of propranolol to patients with ischemic heart disease].

As many as 314 patients with functional class I-III ischemic heart disease (IHD) who had been placed on a long-term (3-year) monotherapy with propranolol were examined. Under a long-term administration of a beta-adrenoblocking agent no suppression has been seen of the contractile capability of the myocardium; there is noted an improvement in hemorheologic disturbances and a significantly greater improvement in the clinical course of the illness--it has been found out the therapy prevents transformation of angina of high effort to angina of low effort.

[The results of the conservative treatment of patients with small-cell lung cancer].

The results of conservative treatment of 246 cases of small-cell cancer of the lung at The All-Union Center for Oncology Research of the USSR Academy of Medical Sciences (1974-1982) are discussed. Survival for two years was registered in 45 cases (18%), 2.5 years--10% and three years--in 7%.