Publications by authors named "Byarugaba Baterana"
Background: The potential effects of SARS-CoV-2 and co-infection on host susceptibility and pathogenesis remain unknown. We aimed to establish the prevalence of malaria and describe the clinical characteristics of SARS-CoV-2 and co-infection in a high-burden malaria setting.
Methods: This was an exploratory prospective, cohort study of patients with COVID-19 who were admitted to hospital in Uganda.
Rationale: Convalescent plasma (CCP) has been studied as a potential therapy for COVID-19, but data on its efficacy in Africa are limited.
Objective: In this trial we set out to determine the efficacy of CCP for treatment of COVID-19 in Uganda.
Measurements: Patients with a positive SARS-CoV-2 reverse transcriptase (RT)-PCR test irrespective of disease severity were hospitalised and randomised to receive either COVID-19 CCP plus standard of care (SOC) or SOC alone.
Introduction: Evidence that supports the use of COVID-19 convalescent plasma (CCP) for treatment of COVID-19 is increasingly emerging. However, very few African countries have undertaken the collection and processing of CCP. The aim of this study was to assess the feasibility of collecting and processing of CCP, in preparation for a randomized clinical trial of CCP for treatment of COVID-19 in Uganda.
View Article and Find Full Text PDFRationale: Detailed data on the characteristics and outcomes of patients with COVID-19 in sub-Saharan Africa are limited.
Objective: We determined the clinical characteristics and treatment outcomes of patients diagnosed with COVID-19 in Uganda.
Measurements: As of the 16 May 2020, a total of 203 cases had been confirmed.