Publications by authors named "Butcher-Danladi Jonathan George"
Article Synopsis
- Tick bites from the ectoparasite Amblyomma variegatum lead to mechanical injuries and undesirable histopathological changes in Yankasa sheep skins, impacting the quality of the resulting leathers.
- A study with infested and control sheep showed that tick bites resulted in significant keratinization and reduced the percentage elongation at break (PEB) of the leather, indicating decreased quality.
- The findings highlight the urgent need for increased awareness about the negative effects of tick infestations on sheep skin quality, which can lead to financial losses due to the production of low-value, unsuitable leathers.
Influence of zinc supplementation on histopathological changes in the stomach, liver, kidney, brain, pancreas and spleen during subchronic exposure of Wistar rats to glyphosate.
Emmanuel Vandi Tizhe Najume Dogon-Giginya Ibrahim Mohammed Yakasai Fatihu Igbokwe Ikechukwu Onyebuchi Butcher Danladi Jonathan George
Comp Clin Path
October 2013
Article Synopsis
- A subchronic toxicity study investigated the effects of glyphosate on various organs in rats and the protective role of zinc when administered prior to glyphosate exposure.
- The study involved exposing rats to two doses of glyphosate for 8 weeks, leading to notable damage in organs like the stomach, liver, kidneys, brain, pancreas, and spleen, particularly at the higher dose of 375 mg/kg.
- Zinc supplementation significantly reduced the harmful histopathological changes caused by glyphosate, showing no alterations in the organ structure of zinc-supplemented rats, highlighting its potential protective effect.
A subchronic toxicity study was carried out to assess hepatic and renal functions of rats during oral exposure to glyphosate with zinc for the period of 8 weeks. Forty-eight Wistar rats used for the study were randomized into six groups of eight Wistar rats each, and each group had equal number of male and female Wistar rats. The Wistar rats administered with distilled water at 2 ml/kg body weight served as the control group (DW); others were administered with zinc at 50 mg/kg body weight (Z) group, glyphosate at 375 mg/kg body weight (G) group, a combination of zinc and glyphosate at 50 and 375 mg/kg body weight, respectively (Z + G), group, glyphosate at 14.
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