Publications by authors named "Bushra H Hamid"
Background: Sentinel lymph node mapping is a minimally invasive surgical staging procedure that allows identification of macro- and micrometastases. The implementation of sentinel lymph node mapping to women with low-grade endometrial cancer allows detection of lymph node metastases and avoids the morbidity of radical pelvic lymphadenectomy. The extent of myometrial invasion is highly predictive of lymph node metastases but is hard to determine precisely preoperatively.
View Article and Find Full Text PDFArticle Synopsis
- The SENTIREC-endo study explores the safety and effectiveness of sentinel lymph node (SLN) mapping in women with early-stage low-grade endometrial cancer, specifically focusing on those with low- and intermediate-risk for lymph node metastases.
- A multicenter study from March 2017 to February 2022 included 627 women, showing a high SLN detection rate of 94.3% and revealing a low overall incidence of lymph node metastases at 9.3%.
- The results indicate minimal postoperative complications (only 8%) and a very low incidence of lymphedema, suggesting that SLN mapping is a safe technique that can improve treatment for low- and intermediate-risk endometrial cancer patients.
Personalized treatment, supported by biomarkers, would improve survival of ovarian cancer patients. RNA molecules are potentially important biomarkers. The Danish CancerBiobank provides an infrastructure for handling and storage of biological material, including RNA, from Danish cancer patients.
View Article and Find Full Text PDF