The potential for false-positive diagnosis of protostrongyliasis by extraction of larvae from feces.

The potential of protostrongylid first-stage larvae (L1) to survive passage through the alimentary canal of non-infected mammals was investigated. Parelaphostrongylus tenuis L1 were collected from feces of an experimentally infected white-tailed deer (Odocoileus virginianus). We utilized two red deer (Cervus elaphus) and four laboratory rats (Rattus norvegicus) which were each fed the L1 of P.

Pain at the end of the stem after revision total knee arthroplasty.

A consecutive series of patients undergoing revision total knee arthroplasty was studied prospectively. Clinical and radiographic assessment was performed preoperatively, 6 and 12 months postoperatively, and annually thereafter. Evaluation consisted of a Knee Society clinical score and assessment of patient satisfaction.

Pulmonary metastasectomy for head and neck cancers.

Background: Distant metastases from carcinomas that arise from the head and neck region are infrequent. The most common site is the lung. To evaluate the results of resection of pulmonary metastases for head and neck cancers, we reviewed our own cases of these metastases.

Seroprevalence of Helicobacter pylori in the adult population of Christchurch: risk factors and relationship to dyspeptic symptoms and iron studies.

Aim: To determine the prevalence of Helicobacter pylori infection in subjects randomly selected from the Christchurch population and to determine the risk factors and symptoms related to the infection.

Methods: A list of names was randomly generated from the 1996 electoral roll and subjects were sequentially contacted and invited to participate. A questionnaire on dyspeptic symptoms was completed and the subject's serum was analysed for H.

Haemochromatosis gene mutations Cys282Tyr and His63Asp are not increased in Type 2 diabetic patients compared with the Canterbury (New Zealand) general population.

Genetic predisposition to haemochromatosis may be an important aetiological factor in some cases of Type 2 diabetes. Our aim was therefore to test the hypothesis that the haemochromatosis gene mutations Cys282Tyr and His63Asp are more prevalent in Type 2 diabetic patients compared with the Canterbury, New Zealand general population. We studied 230 consecutive patients referred to the Diabetes Services with age > or = 30 years and considered to have Type 2 diabetes.

Pulmonary metastases from soft tissue sarcoma: analysis of patterns of diseases and postmetastasis survival.

Objective: To report the patterns of disease and postmetastasis survival for patients with pulmonary metastases from soft tissue sarcoma in a large group of patients treated at a single institution. Clinical factors that influence postmetastasis survival are analyzed.

Summary Background Data: For patients with soft tissue sarcoma, the lungs are the most common site of metastatic disease.

The management of unicentric and multicentric Castleman's disease: a report of 16 cases and a review of the literature.

Background: Castleman's disease (CD), or angiofollicular lymph node hyperplasia, creates both diagnostic and therapeutic dilemmas for most physicians. For patients with this rare and poorly understood disease, the optimal therapy is unknown. The authors report their experience during the years 1986-1997 with this uncommon clinicopathologic entity.

The Program Environment Scale: assessing client perceptions of community-based programs for the severely mentally ill.

The Program Environment Scale (PES) was developed for use with clients of community-based programs for the severely mentally ill. It is intended to fill the gap in available tools for assessing clients' perceptions of program functioning as it affects their "quality of life" in a program. Formal pretests were conducted with 121 clients at 12 randomly selected programs near Washington, DC.

Intestinal permeability after early postoperative enteral nutrition in patients with upper gastrointestinal malignancy.

Background: Increased intestinal permeability may lead to sepsis in resected upper gastrointestinal (GI) cancer patients. This study sought to determine whether these patients demonstrated increased intestinal permeability and if early postoperative enteral nutrition would alter this result.

Methods: Nineteen patients undergoing complete resection of upper GI malignancy were randomized into two groups: the nonfed group received IV crystalloid, and the fed group started enteral nutrition by jejunostomy on postoperative day (POD) 1.

Growth hormone, alone and in combination with insulin, increases whole body and skeletal muscle protein kinetics in cancer patients after surgery.

Objective: To investigate the impact of growth hormone, alone and in combination with insulin, on the protein kinetics of patients with upper gastrointestinal (GI) tract cancer who have undergone surgery and are receiving total parenteral nutrition (TPN).

Summary Background Data: Patients with malignancies of the upper GI tract are at increased risk for malnutrition and perioperative death and complications. Standard nutritional support has not significantly altered outcome.

Pulmonary metastasectomy for testicular germ cell tumors: a 28-year experience.

Background: The role of surgery in patients with pulmonary metastatic germ cell tumors has been evolving since the 1970s. To evaluate the results of pulmonary resection, we reviewed our 28-year experience.

Methods: Between July 1967 and May 1995, 157 patients with testicular germ cell tumors underwent pulmonary resections for suspected metastases.

The significance of haemochromatosis gene mutations in the general population: implications for screening.

Background: Haemochromatosis is associated with mutations in the HFE gene but the significance of these mutations in the general population is unknown.

Aims: To determine the frequency of HFE gene mutations in the general population, their effect on serum iron indexes, and their role in screening for haemochromatosis.

Methods: Deoxyribonucleic acid (DNA) from 1064 randomly selected subjects was analysed for the C282Y and H63D mutations in the HFE gene.

Geographical, seasonal, and sex dynamics of Shipleya inermis (Cestoidea: Dioecocestidae) in Limnodromus griseus Gmelin (Aves: Charadriiformes).

We recovered the cestode Shipleya inermis from 79 of 82 short-billed dowitchers, Limnodromus griseus Gmelin, collected at various locations and times along their migratory route. Previous studies that examined various aspects of the cestode's biology were limited to North America. Data collected from North and South America in the present study provide new information on the geographical and seasonal distribution of this cestode.

Paraliga charadrii n. sp. (Cestoda: Dilepididae) from the semipalmated plover, Charadrius semipalmatus Bonaparte (Aves: Charadriiformes).

Paraliga charadrii n. sp. (Dilepididae) is described from the small intestine of the semipalmated plover Charadrius semipalmatus (Charadriidae) collected from the Bay of Fundy, New Brunswick, Canada.

Cytostatic lung perfusion by use of an endovascular blood flow occlusion technique.

Background: Different modalities of cytostatic lung perfusion were compared regarding plasma and tissue drug concentrations to assess the efficacy of an endovascular blood flow occlusion technique.

Methods: A cytostatic lung perfusion study with doxorubicin hydrochloride was performed on large white pigs (n = 12). Plasma and tissue concentrations of doxorubicin were compared for isolated lung perfusion with open cannulation (ILP), blood flow occlusion perfusion with open cannulation of the pulmonary artery alone (BFO), and intravenous drug administration (i.

Prolonged air leak following radical upper lobectomy: an analysis of incidence and possible risk factors.

Study Objectives: To examine the incidence and clinical significance of prolonged air leak (PAL) in patients undergoing radical upper lobectomy and to determine potential risk factors for PAL in this group of patients.

Design: Retrospective review of a prospective database.

Setting: Experience of one thoracic surgeon at a tertiary care cancer center.

Resection of metastatic renal cell carcinoma.

Purpose: Resection of solitary metastases from renal cell carcinoma (RCC) is associated with a 5-year survival rate of 35% to 50%. Selection criteria are not well defined.

Patients And Methods: We retrospectively analyzed our experience with 278 patients with recurrent RCC from 1980 to 1993.

Impact of zidovudine plus lamivudine or zalcitabine on health-related quality of life.

Objective: To assess the impact of treatment with zidovudine plus lamivudine or zalcitabine on health-related quality of life (HRQOL) in patients with HIV.

Design: HRQOL assessments were conducted as part of a double-blind, randomized, 24-week (extended to 52 wk) efficacy and safety study. The Medical Outcomes Study HIV Health Survey (MOS-HIV), which assesses 10 physical and psychological domains of HRQOL, was self-administered by patients at baseline and at weeks 16, 32, 52, or at treatment discontinuation.

Isolated lung perfusion: single-pass system versus recirculating blood perfusion in pigs.

Background: Cytostatic isolated lung perfusion has been advocated for treating pulmonary metastasis of soft tissue sarcoma. Different techniques of isolated lung perfusion have been developed.

Methods: Isolated lung perfusion with and without doxorubicin was performed on white pigs during 15 minutes either by a single-pass system (n = 7) or by a recirculating-blood perfusion system (n = 7).

The influence of iron on chronic hepatitis C.

It has recently been suggested that the hepatic iron concentration can be used to predict the response to interferon in patients with chronic hepatitis C. An hepatic iron concentration greater than 1100 microg/g appears to identify a group of patients that are unlikely to respond to alpha-interferon. It is not known whether this relationship can be explained by associated variables such as age, gender or disease severity or whether the hepatic iron concentration itself influences the response to interferon.

The total volar forearm musculocutaneous free flap for reconstruction of extended forequarter amputations.

Forequarter amputation is performed for resection of large, invasive tumors of the shoulder girdle region. A substantial defect can usually be closed with local or regional flaps; however, a subset of the forequarter amputation group has emerged at this institution with more complex issues. These patients have extensively more invasive posterior tumors, some with chest wall/rib invasion.

Gallbladder polyps: prospective study.

The aim of this study was to describe the natural history of gallbladder polyps. Thirty-eight subjects who had been previously identified as having gallbladder polyps in an epidemiologic study of gallstone prevalence in 627 diabetic subjects and matched controls were followed longitudinally. Follow-up sonograms were obtained on 33 and 22 of the 38 subjects at 2 and 5 years, respectively.

Primary sarcomas of the mediastinum: results of therapy.

Unlabelled: Primary sarcomas of the mediastinum are rare, and data concerning treatment and results of therapy are sparse.

Objective: To assess presentation, management, prognostic factors, and survival in mediastinal sarcomas.

Methods: We reviewed our experience with 47 patients with the diagnosis of primary sarcoma of the mediastinum.