Phonological Feature Abstraction Before 6 Months: Amodal Recognition of Place of Articulation Across Multiple Consonants.

The classical view is that perceptual attunement to the native language, which emerges by 6-10 months, developmentally precedes phonological feature abstraction abilities. That assumption is challenged by findings from adults adopted into a new language environment at 3-5 months that imply they had already formed phonological feature abstractions about their birth language prior to 6 months. As phonological feature abstraction had not been directly tested in infants, we examined 4-6-month-olds' amodal abstraction of the labial versus coronal place of articulation distinction between consonants.

Maternal input, not transient elevated depression and anxiety symptoms, predicts 2-year-olds' vocabulary development.

Both the quantity and quality of the maternal language input are important for early language development. However, depression and anxiety can negatively impact mothers' engagement with their infants and their infants' expressive language abilities. Australian mother-infant dyads ( = 30) participated in a longitudinal study examining the effect of maternal language input when infants were 24 and 30 months and maternal depression and anxiety symptoms on vocabulary size.

Shaping linguistic input in parent-infant interactions: The influence of the Infant's temperament.

Parent-infant interactions highlight the role of parental input, considering both the quality, infant-directed speech, and quantity of interactions, adult words and communicative turns, in these interactions. However, communication is bidirectional, yet little is known about the infant's role in these interactions. This study (n = 35 4-month-old infants) explores how infant-directed speech, the number of adult words and turn-taking (both measured by the LENA system) are correlated with infants' temperament.

Atypical low-frequency cortical encoding of speech identifies children with developmental dyslexia.

Slow cortical oscillations play a crucial role in processing the speech amplitude envelope, which is perceived atypically by children with developmental dyslexia. Here we use electroencephalography (EEG) recorded during natural speech listening to identify neural processing patterns involving slow oscillations that may characterize children with dyslexia. In a story listening paradigm, we find that atypical power dynamics and phase-amplitude coupling between delta and theta oscillations characterize dyslexic versus other child control groups (typically-developing controls, other language disorder controls).

Leveraging low-cost sensors to predict nitrogen dioxide for epidemiologic exposure assessment.

Background: Statistical models of air pollution enable intra-urban characterization of pollutant concentrations, benefiting exposure assessment for environmental epidemiology. The new generation of low-cost sensors facilitate the deployment of dense monitoring networks and can potentially be used to improve intra-urban models of air pollution.

Objective: Develop and evaluate a spatiotemporal model for nitrogen dioxide (NO) in the Puget Sound region of WA, USA for the Adult Changes in Thought Air Pollution (ACT-AP) study and assess the contribution of low-cost sensor data to the model's performance through cross-validation.

Impact of a pharmacy-driven culture callback protocol on antimicrobial therapy optimization in the emergency department.

Background: Timely assessment of cultures for discharged patients from the emergency department (ED) is crucial for quality patient care and safety outcomes. The purpose of this study was to evaluate the efficacy of implementing a standardized pharmacy-driven culture callback protocol on antimicrobial therapy optimization for patients discharged from the ED with positive urine, blood, or sexually transmitted infection (STI) cultures.

Objective: To assess the impact of a pharmacy-driven culture callback process on antimicrobial therapy optimization in the ED.

Evaluating low-cost monitoring designs for PM exposure assessment with a spatiotemporal modeling approach.

Determining the most feasible and cost-effective approaches to improving PM exposure assessment with low-cost monitors (LCMs) can considerably enhance the quality of its epidemiological inferences. We investigated features of fixed-site LCM designs that most impact PM exposure estimates to be used in long-term epidemiological inference for the Adult Changes in Thought Air Pollution (ACT-AP) study. We used ACT-AP collected and calibrated LCM PM measurements at the two-week level from April 2017 to September 2020 (N of monitors [measurements] = 82 [502]).

The bacterial replication origin BUS promotes nucleobase capture.

Genome duplication is essential for the proliferation of cellular life and this process is generally initiated by dedicated replication proteins at chromosome origins. In bacteria, DNA replication is initiated by the ubiquitous DnaA protein, which assembles into an oligomeric complex at the chromosome origin (oriC) that engages both double-stranded DNA (dsDNA) and single-stranded DNA (ssDNA) to promote DNA duplex opening. However, the mechanism of DnaA specifically opening a replication origin was unknown.

Seeing a Talking Face Matters: Gaze Behavior and the Auditory-Visual Speech Benefit in Adults' Cortical Tracking of Infant-directed Speech.

In face-to-face conversations, listeners gather visual speech information from a speaker's talking face that enhances their perception of the incoming auditory speech signal. This auditory-visual (AV) speech benefit is evident even in quiet environments but is stronger in situations that require greater listening effort such as when the speech signal itself deviates from listeners' expectations. One example is infant-directed speech (IDS) presented to adults.

Does Musicality Assist Foreign Language Learning? Perception and Production of Thai Vowels, Consonants and Lexical Tones by Musicians and Non-Musicians.

The music and spoken language domains share acoustic properties such as fundamental frequency (f0, perceived as pitch), duration, resonance frequencies, and intensity. In speech, the acoustic properties form an essential part in differentiating between consonants, vowels, and lexical tones. This study investigated whether there is any advantage of musicality in the perception and production of Thai speech sounds.

Effects of maternal depression on maternal responsiveness and infants' expressive language abilities.

High levels of maternal responsiveness are associated with healthy cognitive and emotional development in infants. However, depression and anxiety can negatively impact individual mothers' responsiveness levels and infants' expressive language abilities. Australian mother-infant dyads (N = 48) participated in a longitudinal study examining the effect of maternal responsiveness (when infants were 9- and 12-months), and maternal depression and anxiety symptoms on infant vocabulary size at 18-months.

Impaired neural entrainment to low frequency amplitude modulations in English-speaking children with dyslexia or dyslexia and DLD.

Neural synchronization to amplitude-modulated noise at three frequencies (2 Hz, 5 Hz, 8 Hz) thought to be important for syllable perception was investigated in English-speaking school-aged children. The theoretically-important delta-band (∼2Hz, stressed syllable level) was included along with two syllable-level rates. The auditory steady state response (ASSR) was recorded using EEG in 36 7-to-12-year-old children.

Infants show enhanced neural responses to musical meter frequencies beyond low-level features.

Music listening often entails spontaneous perception and body movement to a periodic pulse-like meter. There is increasing evidence that this cross-cultural ability relates to neural processes that selectively enhance metric periodicities, even when these periodicities are not prominent in the acoustic stimulus. However, whether these neural processes emerge early in development remains largely unknown.

Seeing a talking face matters: Infants' segmentation of continuous auditory-visual speech.

Visual speech cues from a speaker's talking face aid speech segmentation in adults, but despite the importance of speech segmentation in language acquisition, little is known about the possible influence of visual speech on infants' speech segmentation. Here, to investigate whether there is facilitation of speech segmentation by visual information, two groups of English-learning 7-month-old infants were presented with continuous speech passages, one group with auditory-only (AO) speech and the other with auditory-visual (AV) speech. Additionally, the possible relation between infants' relative attention to the speaker's mouth versus eye regions and their segmentation performance was examined.

Language specificity in cortical tracking of speech rhythm at the mora, syllable, and foot levels.

Recent research shows that adults' neural oscillations track the rhythm of the speech signal. However, the extent to which this tracking is driven by the acoustics of the signal, or by language-specific processing remains unknown. Here adult native listeners of three rhythmically different languages (English, French, Japanese) were compared on their cortical tracking of speech envelopes synthesized in their three native languages, which allowed for coding at each of the three language's dominant rhythmic unit, respectively the foot (2.

Seeing a talking face matters: The relationship between cortical tracking of continuous auditory-visual speech and gaze behaviour in infants, children and adults.

An auditory-visual speech benefit, the benefit that visual speech cues bring to auditory speech perception, is experienced from early on in infancy and continues to be experienced to an increasing degree with age. While there is both behavioural and neurophysiological evidence for children and adults, only behavioural evidence exists for infants - as no neurophysiological study has provided a comprehensive examination of the auditory-visual speech benefit in infants. It is also surprising that most studies on auditory-visual speech benefit do not concurrently report looking behaviour especially since the auditory-visual speech benefit rests on the assumption that listeners attend to a speaker's talking face and that there are meaningful individual differences in looking behaviour.

The tone atlas of perceptual discriminability and perceptual distance: Four tone languages and five language groups.

Some prior investigations suggest that tone perception is flexible, reasonably independent of native phonology, whereas others suggest it is constrained by native phonology. We address this issue in a systematic and comprehensive investigation of adult tone perception. Sampling from diverse tone and non-tone speaking communities, we tested discrimination of the three major tone systems (Cantonese, Thai, Mandarin) that dominate the tone perception literature, in relation to native language and language experience as well as stimulus variation (tone properties, presentation order, pitch cues) using linear mixed effect modelling and multidimensional scaling.

Language development in infants with hearing loss: Benefits of infant-directed speech.

The majority of infants with permanent congenital hearing loss fall significantly behind their normal hearing peers in the development of receptive and expressive oral communication skills. Independent of any prosthetic intervention ("hardware") for infants with hearing loss, the social and linguistic environment ("software") can still be optimal or sub-optimal and so can exert significant positive or negative effects on speech and language acquisition, with far-reaching beneficial or adverse effects, respectively. This review focusses on the nature of the social and linguistic environment of infants with hearing loss, in particular others' speech to infants.

Seasonal calibration of the end-cretaceous Chicxulub impact event.

The end-Cretaceous Chicxulub impact triggered Earth's last mass-extinction, extinguishing ~ 75% of species diversity and facilitating a global ecological shift to mammal-dominated biomes. Temporal details of the impact event on a fine scale (hour-to-day), important to understanding the early trajectory of mass-extinction, have largely eluded previous studies. This study employs histological and histo-isotopic analyses of fossil fish that were coeval with a unique impact-triggered mass-death assemblage from the Cretaceous-Paleogene (KPg) boundary in North Dakota (USA).

The Landscape of Perception: Racial Differences in How Disability Is Viewed Among Older-Adult Cancer Survivors.

This paper compares disability perceptions of Black with white older cancer survivors' to document racial disparities in these perceptions and the factors that contribute to them. The data are from a randomly selected tumor registry sample of 321 older adult cancer survivors from an NCI funded study. OLS regression models of disability perceptions, nested by race, examined the effects cancer and non-cancer health factors along with important covariates.

Validation of the plasmid study to relate DNA damaging effects of radionuclides to those from external beam radiotherapy.

Introduction: The biological consequences of absorbed radiation doses are ill-defined for radiopharmaceuticals, unlike for external beam radiotherapy (EBRT). A reliable assay that assesses the biological consequences of any radionuclide is much needed. Here, we evaluated the cell-free plasmid DNA assay to determine the relative biological effects of radionuclides such as Auger electron-emitting [Ga]GaCl or [In]InCl compared to EBRT.

Finding Purpose in the Conservation of Biodiversity by the Commingling of Science and Ethics.

Averting the biodiversity crisis requires closing a gap between how humans tend to behave, individually and collectively, and how we ought to behave-"ought to" in the sense of behaviors required to avert the biodiversity crisis. Closing that gap requires synthesizing insight from ethics with insights from social and behavioral sciences. This article contributes to that synthesis, which presents in several provocative hypotheses: (i) Lessening the biodiversity crisis requires promoting pro-conservation behavior among humans.

Acoustic features of infant-directed speech to infants with hearing loss.

This study investigated the effects of hearing loss and hearing experience on the acoustic features of infant-directed speech (IDS) to infants with hearing loss (HL) compared to controls with normal hearing (NH) matched by either chronological or hearing age (experiment 1) and across development in infants with hearing loss as well as the relation between IDS features and infants' developing lexical abilities (experiment 2). Both experiments included detailed acoustic analyses of mothers' productions of the three corner vowels /a, i, u/ and utterance-level pitch in IDS and in adult-directed speech. Experiment 1 demonstrated that IDS to infants with HL was acoustically more variable than IDS to hearing-age matched infants with NH.