Fantastic wetlands and why to monitor them: Demonstrating the social and financial benefit potential of methane abatement through salt marsh restoration.

Salt marsh restoration has the potential to reduce greenhouse gas emissions thereby providing an opportunity for blue carbon crediting, but implementation has been limited to date because of insufficient data and validation. In this paper, we demonstrate the potential scale of methane emissions that could be avoided if salinity-reducing impairments are mitigated by applying findings from six salt marsh restoration sites in Massachusetts combined with a previously demonstrated application of the salt marsh salinity-methane relationship. We used calculations of these avoided emissions to estimate the social benefit of salt marsh restoration by calculating avoided costs.

Identifying the criteria for community-centred Life Cycle Sustainability Assessment of estate regeneration schemes.

Identifying the overall environmental, and socioeconomic impacts of different estate regeneration scenarios can contribute to the overall sustainability of such schemes. Life Cycle Sustainability Assessment (LCSA) is an appropriate tool for assessing holistic sustainability. To achieve resilient societies, the interests of communities should be considered in decision making.

Coupling finite and boundary element methods to solve the Poisson-Boltzmann equation for electrostatics in molecular solvation.

The Poisson-Boltzmann equation is widely used to model electrostatics in molecular systems. Available software packages solve it using finite difference, finite element, and boundary element methods, where the latter is attractive due to the accurate representation of the molecular surface and partial charges, and exact enforcement of the boundary conditions at infinity. However, the boundary element method is limited to linear equations and piecewise constant variations of the material properties.

This land is your land, this could be marsh land: Property parcel characteristics of marsh migration corridors in Rhode Island, USA.

Salt marshes, critical habitats offering many ecosystem services, are threatened by development, accelerated sea level rise (SLR) and other anthropogenic stressors that are projected to worsen. As seas rise, some salt marshes can migrate inland if there is adjacent, permeable, undeveloped land available. Facilitating marsh migration is necessary for coastal resilience efforts, but extensive coastal development can make finding suitable migration corridors challenging.

Hazardous and contaminated sites within salt marsh migration corridors in Rhode Island, USA.

As salt marshes attempt to migrate upland due to sea level rise, they will encounter many kinds of land development and infrastructure in highly populated, urbanized coastal communities. Hazardous and contaminated sites (HCSs) -- facilities and infrastructure that store, use, or release harmful substances -- are particularly concerning obstacles to salt marsh migration because of their potential to release contaminants if their structural integrity is compromised. Inventorying HCSs within migration pathways can inform coastal resilience planning.

Microbial Community Interactions Are Sensitive to Small Changes in Temperature.

Microbial communities are essential for human and environmental health, often forming complex interaction networks responsible for driving ecosystem processes affecting their local environment and their hosts. Disturbances of these communities can lead to loss of interactions and thereby important ecosystem functionality. The research on what drives interactions in microbial communities is still in its infancy, and much information has been gained from the study of model communities.

Zinc-dependent multimerization of mutant calreticulin is required for MPL binding and MPN pathogenesis.

Calreticulin (CALR) is mutated in the majority of JAK2/MPL-unmutated myeloproliferative neoplasms (MPNs). Mutant CALR (CALRdel52) exerts its effect by binding to the thrombopoietin receptor MPL to cause constitutive activation of JAK-STAT signaling. In this study, we performed an extensive mutagenesis screen of the CALR globular N-domain and revealed 2 motifs critical for CALRdel52 oncogenic activity: (1) the glycan-binding lectin motif and (2) the zinc-binding domain.

CAFE: a software suite for analysis of paired-sample transposon insertion sequencing data.

Summary: Sequencing of transposon insertion libraries is used to determine the relative fitness of individual mutants at a large scale. However, there is a lack of tools for specifically analyzing data from such experiments with paired sample designs. Here, we introduce CAFE-Coefficient-based Analysis of Fitness by read Enrichment-a software package that can analyze data from paired transposon mutant sequencing experiments, generate fitness coefficients for each gene and condition and perform appropriate statistical testing on these fitness coefficients.

Finite element approximation of the Laplace-Beltrami operator on a surface with boundary.

We develop a finite element method for the Laplace-Beltrami operator on a surface with boundary and nonhomogeneous Dirichlet boundary conditions. The method is based on a triangulation of the surface and the boundary conditions are enforced weakly using Nitsche's method. We prove optimal order a priori error estimates for piecewise continuous polynomials of order in the energy and norms that take the approximation of the surface and the boundary into account.

A cut finite element method for elliptic bulk problems with embedded surfaces.

We propose an unfitted finite element method for flow in fractured porous media. The coupling across the fracture uses a Nitsche type mortaring, allowing for an accurate representation of the jump in the normal component of the gradient of the discrete solution across the fracture. The flow field in the fracture is modelled simultaneously, using the average of traces of the bulk variables on the fractures.

Data assimilation for the heat equation using stabilized finite element methods.

We consider data assimilation for the heat equation using a finite element space semi-discretization. The approach is optimization based, but the design of regularization operators and parameters rely on techniques from the theory of stabilized finite elements. The space semi-discretized system is shown to admit a unique solution.

Edge-based nonlinear diffusion for finite element approximations of convection-diffusion equations and its relation to algebraic flux-correction schemes.

For the case of approximation of convection-diffusion equations using piecewise affine continuous finite elements a new edge-based nonlinear diffusion operator is proposed that makes the scheme satisfy a discrete maximum principle. The diffusion operator is shown to be Lipschitz continuous and linearity preserving. Using these properties we provide a full stability and error analysis, which, in the diffusion dominated regime, shows existence, uniqueness and optimal convergence.

Concussed athletes are more prone to injury both before and after their index concussion: a data base analysis of 699 concussed contact sports athletes.

Background: Ice hockey and football players suffering concussions might have an increased risk for injuries afterwards. We aimed to investigate if concussions predisposed athletes for subsequent sport injuries.

Methods: Patient data were obtained from a data base established at the University Hospital in Umea, Sweden.

Pulmonary artery diameters, cross sectional areas and area changes measured by cine cardiovascular magnetic resonance in healthy volunteers.

Background: We measured by cine cardiovascular magnetic resonance (CMR) main and branch pulmonary artery diameters and cross sectional areas in diastole and systole in order to establish normal ranges and the effects on them of age, gender and body surface area (BSA). Documentation of normal ranges provides a reference for research and clinical investigation in the fields of congenital heart disease, pulmonary hypertension and connective tissue disorders.

Methods: We recruited 120 healthy volunteers: ten males (M) and ten females (F) in each decile between 20 and 79 years, imaging them in a 1.

Aortic root measurement by cardiovascular magnetic resonance: specification of planes and lines of measurement and corresponding normal values.

Background: Cardiovascular magnetic resonance is widely used for aortic root visualization and measurement, but methods still need to be standardized. Our aim was to identify appropriate planes of acquisition and lines of measurement and record corresponding normal values.

Methods And Results: We studied 120 healthy volunteers, 10 of each gender in each decile between 20 and 80 years, by using a 1.

Multielement analysis of coal by ICP techniques using solution nebulization and laser ablation.

The combination of inductively coupled plasma atomic emission spectrometry and high resolution inductively coupled plasma mass spectrometry for the determination of 70 elements in coal were studied. Four microwave-assisted digestion procedures with different dissolution mixtures (nitric and hydrofluoric acids, aqua regia and hydrogen peroxide), lithium metaborate fusion with and without previous sample ashing as well as direct sampling by laser ablation (LA) have been tested. Examples of spectral interferences are given and different correction procedures are discussed.

Difficulties for primary health care staff in interpreting bacterial findings on a device for simplified urinary culture.

The reliability of interpretations of findings from dip-slide devices for culturing urine was investigated in a national Swedish external quality assessment (EQA) programme. Also investigated was the extent of improvement in the examination procedure achieved through personnel training programmes and information. According to Swedish national recommendations, dip-slide should only be used in primary health care (PHC) in cases of uncomplicated urinary tract infection (UTI) in females of childbearing age.

Between orientalism and normalization: cross-cultural lessons from Japan for a critical history of psychology.

Cross-cultural research performs a vital role within the confirmation of psychological "truths." Its differentiations work simultaneously to establish their general applicability and the superiority of Anglo-U.S.

Cardiovascular magnetic resonance, fibrosis, and prognosis in dilated cardiomyopathy.

Objectives: We studied the prognostic implications of midwall fibrosis in dilated cardiomyopathy (DCM) in a prospective longitudinal study.

Background: Risk stratification of patients with nonischemic DCM in the era of device implantation is problematic. Approximately 30% of patients with DCM have midwall fibrosis as detected by late gadolinium-enhancement (LGE) cardiovascular magnetic resonance (CMR), which may increase susceptibility to arrhythmia and progression of heart failure.

Domestic violence and minoritisation: legal and policy barriers facing minoritized women leaving violent relationships.

This article on service responses to women of African, African-Caribbean, Irish, Jewish and South Asian backgrounds facing domestic violence draws on our recently completed study based in Manchester, UK () [Batsteeler, J., Burman, E., Chantler, K.

Glagov remodeling of the atherosclerotic aorta demonstrated by cardiovascular magnetic resonance: the CORDA asymptomatic subject plaque assessment research (CASPAR) project.

Background: Aortic atherosclerosis and coronary artery disease (CAD) are closely linked. Early detection of aortic atherosclerosis with the adoption of appropriate preventive measures may therefore help to reduce mortality and morbidity related to CAD. Arterial remodeling, by which the wall adapts to physiological or pathological insults by a change in vessel size, is being increasingly recognized as an important aspect of atherosclerosis.