[Prospects of clinical application of cilostazol for peripheral artery disease].

This article presents a review of the literature on studying Cilostazol, a type 3 phosphodiesterase inhibitor, also providing the Russian and foreign statistics on the prevalence of peripheral artery disease. It is underlined that the majority of patients with peripheral artery disease have atherosclerotic lesions in the coronary and cerebral vascular basins. Cilostazol deservedly occupies the first lines in the sections of pharmacotherapy for intermittent claudication in international and Russian consensus documents on peripheral artery disease.

[Differentiated treatment of patients with diabetic foot syndrome at the stage of specialized surgical care].

Aim: To assess 1-year results of differentiated treatment of patients with diabetic foot syndrome (DFS) who were included into 3-year register of diabetic foot outpatient practice (DFOP).

Material And Methods: It was performed retrospective analysis of 570 patients with DFS (2015-2017): group I - neuropathic form (n=285), group II - neuroischemic form (n=285). Patients were classified according to Texas grade.

[The role of the vascular surgeon in improvement of organization of dialysis help].

Analysed herein are one-year results of formation of arteriovenous fistulas in 109 patients with end-stage chronic renal failure, as well as therapeutic decision-making after angiosurgical counselling of 144 patients presenting with 'problem' permanent vascular accesses. The counselling and formation of arteriovenous fistulas were carried out in conditions of interdepartmental collaboration between outpatient centres dealing with haemodialysis and vascular surgeons specialized in ultrasound mapping of peripheral vessels and performing different variants of arteriovenous fistulas. The angiosurgical care was as close to the patient as possible.

[Comparative 3-year results of phlebectomy and thermal ablation for lower limb varicose veins].

The study was aimed at comparing clinical and ultrasonographic results during 3 years of postoperative follow up of patients presenting with lower limb varicose veins (LLVV) and subjected to either surgical or thermal-ablation procedures for removal of pathological reflux along the great saphenous vein (GSV) within the femur The study included a total of 185 patients with clinical class C2-3 LLVV in the system of the GSV. The patients were divided into three groups: Group One consisted of 63 patients subjected to short stripping of the GSV trunk + treatment of the perforant veins (66.7%); Group Two comprised 61 patients undergoing endovenous laser coagulation (EVLC) of the GSV trunk + EVLC of the perforant veins (73.

[Administration of Neovasculgen agent for treatment of a patient with neuroischaemic form of diabetic foot syndrome].

Presented herein is a case report concerning successful treatment of a patient with the neuroischaemic form of diabetic foot syndrome using Neovasculgen(®) agent. This case by salvage of the supporting leg could have been considered unpromising without the use of the methods of therapeutic angiogenesis. The use of Neovasculgen(®) made it possible to obtain an optimal result with rehabilitation of the patient and preserving the initial level of his quality of life.

[Russian observational programme SPEKTR: analysis of age-specific structure of patients with chronic venous diseases].

The authors studied the age-related structure of 864 patients with chronic venous diseases (CVD) by means of analysing the database of the Russian Programme SPEKTR (2011-2012). Most often special medical care was sought by persons of able-bodied age (31-60 years): men - 60.6%, women - 63.

[Evolution of ultrasonic indices of the heart and arteriovenous fistulas in patients on chronic haemodialysis].

The authors assessed the ultrasonic evolution of haemodynamics of arteriovenous fistulas (AVFs), cardiohaemodynamics, and the dimensions of the heart chambers in a total of thirty-five patients presenting with terminal chronic renal insufficiency (TCRI) and being on chronic haemodialysis (CHD). A further thirteen patients without TCRI composed the control group. The TCRI patients were subdivided into two groups: Group One (n=20) with a distal variant of the Cimino-type AVF, 21 vascular accesses, and Group Two (n=15) with a proximal variant of AFV, 16 accesses using a synthetic vascular prosthesis (SVP).

[Compression therapy as a method of choice in treatment of chronic diseases of lower limb veins].

Aim: To assess safety, clinical efficacy, and the level of patients' compliance for compression knitted panty-hose VENOTEKS THERAPY Clinic 2 article 203 in therapy of chronic venous diseases (CVD).

Material: Sixty 18-to-65-year-old female patients with C2-C4 CVD according to the CEAP classification.

Methods: clinical, laboratory, instrumental.

Surgical correction of varicose vein disease under micronized diosmin protection (results of the Russian multicenter controlled trial DEFANS).

The paper presents the results of DEFANS trial (Detralex - assessment of efficacy and safety for combined phlebectomy). The study enrolled 245 patients with varicose vein disease, who underwent unilateral combined phlebectomy. The main group (n=200) received micronized diosmin (Detralex, 1000 mg/day) for 2 weeks before and 30 days after the procedure; control group (n=45) did not receive Detralex in pre- and postoperative period.

The five-year results of reconstructive surgery for critical lower limb ischemia.

This paper analyzes the immediate and long-term (5-year), results of 251 reconstructive operations accomplished for critical lower limb ischemia in 240 patients (stage III chronic arterial insufficiency was present in 135 and stage IV in 105 patients), with introduction of the unified criteria. The outcomes were compared in patients who had undergone revascularization above the Poupart's ligament -- 149 cases (100 cases of proximal reconstruction and 49 of two-level reconstruction) and beneath the Poupart's ligament (102 cases) as dependent on the stage and character of reattachment of the limb peripheral system. The study of the changes in the patients' status, the shifts in hemodynamics, the cumulative bypass patency and limb salvage has revealed the great priority of the choice of two-level reconstructions in patients with multilevel occlusions in stage IV chronic limb arterial insufficiency.

[Specialized outpatient care for patients with initial forms of lower limb chronic venous insufficiency].

Authors present 7-year follow up of 567 patients with initial forms of chronic venous insufficiency (CVI) of lower extremities (442 patients with C-1 class and 125 patients with C-2 class). The analysis of individual clinical and ultrasonic data has shown wide variability and the lack of specificity in CVI symptomatology. Ultrasonic investigation revealed veno-venous reflux in 74.

[Diabetic foot: organisational and clinical approaches].

Pilot results of introduction of new principles of medical care organization for patients with diabetic foot syndrome (DFS) are summarized. Experience in combined treatment of 287 patients with purulent-necrotic forms of DFS is analyzed. Surgical policy was standardized and lied in combined therapy and choice of optimal scope of surgical treatment.

[Procedure in severe ischemia of the extremities in patients with obliterating arterial diseases].

The authors' experience with the treatment of 134 patients enabled them to formulate indications for sympathectomy, reconstructive operations and primary amputations.

[Transcatheteral intra-arterial infusion of drug mixtures in the treatment of severe ischemia of the lower limbs].

Under analysis were results of the treatment of 53 patients with severe ischemic states of lower extremities by the method of transcatheteral intraarterial infusions of drugs. Duration of the treatment was from 7 to 50 days. The composition of the mixtures was chosen individually.

[Complications of subclavian vein punctures and catheterization and the means for their prevention].

The analysis and systematization of errors and complications of punctures and catheterization of subclavian veins in 406 patients have been performed. Complications due to the technique of punctures and catheterization were recorded in 47 patients (11.6%).