Publications by authors named "Burillo M"

A prototype of a picosecond x-ray streak camera has been developed and tested by Commissariat à l'Énergie Atomique et aux Énergies Alternatives to provide plasma-diagnostic support for the Laser Megajoule. We report on the measured performance of this streak camera, which almost fulfills the requirements: 50-μm spatial resolution over a 15-mm field in the photocathode plane, 17-ps temporal resolution in a 2-ns timebase, a detection threshold lower than 625 nJ/cm in the 0.05-15 keV spectral range, and a dynamic range greater than 100.

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The Laser Megajoule (LMJ) facility located at CEA/CESTA started to operate in the early 2014 with two quadruplets (20 kJ at 351 nm) focused on target for the first experimental campaign. We present here the first set of gated x-ray imaging (GXI) diagnostics implemented on LMJ since mid-2014. This set consists of two imaging diagnostics with spatial, temporal, and broadband spectral resolution.

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Commissariat à l'Énergie Atomique et aux Énergies Alternatives has developed the ARGOS X-ray framing camera to perform two-dimensional, high-timing resolution imaging of an imploding target on the French high-power laser facility Laser MegaJoule. The main features of this camera are: a microchannel plate gated X-ray detector, a spring-loaded CCD camera that maintains proximity focus in any orientation, and electronics packages that provide remotely-selectable high-voltages to modify the exposure-time of the camera. These components are integrated into an "air-box" that protects them from the harsh environmental conditions.

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Article Synopsis
  • The study focused on the presence of anti-p53 CD8+ T cells in breast cancer patients, which are important for developing targeted therapies against tumors where the p53 protein is overexpressed.
  • Researchers used multicolor flow cytometry to measure the concentration of these T cells in patients, finding a significant presence in those with the HLA A2.1 molecule.
  • Results showed a specific immunological response in breast cancer patients, suggesting potential for p53-based vaccines, though further research is needed to confirm these findings.
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