Medium vessel occlusions in the drip-and-ship model: Clinical vs. hub CTP-supported decision making.

Introduction: Mechanical thrombectomy (MT) for medium vessel occlusions (MeVO) is emerging as a promising treatment in acute stroke. We aim to evaluate the utility of additional imaging (CTP) in patients with MeVOs who received thrombolysis at a spoke hospital and were transferred to the hub.

Methods: This was a retrospective review of prospectively collected data from April 2018 to June 2023.

Successful Long-Term Management of NF1 Congenital Tibial Dysplasia with Prophylactic Bypass Graft and Bracing: A Case Report.

Case: An 8-year-old girl with NF1 and congenital tibial dysplasia with significant bilateral tibial bowing underwent McFarland procedures. Now age 22 with 14-year follow-up indicating sustained correction and healing of her bilateral limb deformities.

Conclusion: This case illustrates the McFarland procedure provided adequate corrective treatment of this deformity and remains a success at long-term follow-up.

Safety of Adjunctive Intraarterial Tenecteplase Following Mechanical Thrombectomy: The ALLY Pilot Trial.

Background: Recent studies suggest that the use of adjunctive intraarterial alteplase after mechanical thrombectomy (MT) may improve outcomes; however, there are limited data on the use of intraarterial tenecteplase, a newer-generation lytic, in this acute ischemic stroke patient population. Here, we evaluate the use of intraarterial tenecteplase in the ALLY pilot study (Adjunctive Intraarterial Tenecteplase Following Mechanical Thrombectomy).

Methods: ALLY was a prospective, single-center, nonrandomized pilot study assessing the feasibility and safety of intraarterial tenecteplase up to 4.

Coping strategies employed by older Nepalese migrant women to manage their mental distress in the UK: A qualitative research.

Introduction: Mental health and wellbeing is a global public health concern. However, there is limited evidence on managing the mental health needs of the Nepalese migrant population in the UK. This paper is focused on exploring coping strategies employed by older Nepalese migrant women in managing their mental distress.

Can all roads lead to competency? School levels effects in Licensing examinations scores.

At the foundation of research concerned with professional training is the idea of an assumed causal chain between the policies and practices of education and the eventual behaviours of those that graduate these programs. In medicine, given the social accountability to ensure that teaching and learning gives way to a health human resource that is willing and able to provide the healthcare that patients and communities need, it is of critical importance to generate evidence regarding this causal relationship. One question that medical education scholars ask regularly is the degree to which the unique features of training programs and learning environments impact trainee achievement of the intended learning outcomes.

Optimising Musculoskeletal Patient Flow Through Digital Triage and Supported Self-Management: A Service Evaluation Set Within Community Musculoskeletal Care.

Introduction: Musculoskeletal (MSK) conditions are one of the leading causes of years of living with disability in the UK, resulting in pressure on the health system and the UK economy. In response to the increasing levels of patients accessing NHS care with MSK conditions across Sandwell and West Birmingham (SWB), a digital triage and self-management tool was implemented in 2023.

Aims: To optimise safety, efficiency, and choice within the community MSK service from the first contact through to specialist MSK care through digital triage and supported self-management.

Clinical Characteristics and Variation in Musculoskeletal Complexity of Different Ethnic Populations Accessing Sandwell and West Birmingham Hospital's MSK Service: A Service Evaluation.

Introduction: Health inequality is a global public health challenge, limited by insufficient high-quality data and analysis. Musculoskeletal (MSK) pain disorders are more prevalent among ethnic minority groups disproportionately affected by socioeconomic disparities and poor health outcomes. Ethnicity data collection enables NHS organisations and policymakers to understand specific healthcare needs and ensure equitable access and care provision.

Exploring the feeding practices of mothers of under-five children and how household members influence exclusive breastfeeding in Jigawa State, Nigeria - A qualitative study.

Child nutrition interventions in low-income settings are variably effective as strategies often focus on primary caregivers, with less attention given to other household members. This study explored the influence of household members on exclusive breastfeeding and the feeding practices of mothers of under-five children in Jigawa State, Northern Nigeria. As part of a cluster randomised controlled trial in Jigawa State, we conducted an ethnographic process evaluation.

Magnetoencephalography studies in migraine and headache disorders: A systematic review.

Background: Understanding the neural mechanisms underlying migraine and other primary headache disorders is critical for the development of long-term cures. Magnetoencephalography (MEG), an imaging modality that measures neuronal currents and cortical excitability with high temporal and superior spatial resolution, has been increasingly used in neurological research. Initial MEG studies showed promise in directly recording cortical spreading depression-a cortical correlate of migraine with aura.

Corporate activities that influence population health: a scoping review and qualitative synthesis to develop the HEALTH-CORP typology.

Introduction: The concept of the commercial determinants of health (CDH) is used to study the actions of commercial entities and the political and economic systems, structures, and norms that enable these actions and ultimately influence population health and health inequity. The aim of this study was to develop a typology that describes the diverse set of activities through which commercial entities influence population health and health equity across industries.

Methods: We conducted a scoping review to identify articles using CDH terms (n = 116) published prior to September 13, 2022 that discuss corporate activities that can influence population health and health equity across 16 industries.

Validation of a Remote Sampling Sensor for Measuring Urine Volume and Nitrogen Concentration in Grazing Dairy Cattle.

The purpose of this research was to validate a urine sensor (Lincoln University PEETER V2.0, Canterbury, New Zealand) that records the time and volume of urination events for dairy cows in addition to collecting a proportional urine sample from all urination events. Sixteen multiparous Holstein × Jersey mid-lactating cows (101 ± 5 days in milk, 498 ± 24.

Combined temperature and salinity effects on the passive sampling of PAHs with an assessment of impacts to petroleum toxicity.

In equilibrium-based passive sampling applications, the accuracy of estimating freely dissolved concentration () of hydrophobic organic compounds (HOCs) relies on the passive sampler-water partition coefficient () values applied. The vast majority of are generated under standard conditions: 20 °C in deionized or freshwater. Few empirically derived values are available for non-standard conditions.

Quality Indicators for the Primary and Community Care of Musculoskeletal Conditions: A Systematic Review.

Objectives: To identify, appraise, and synthesize common themes from quality indicator (QI) sets designed for the assessment, management, and rehabilitation of musculoskeletal (MSK) conditions in primary and community care contexts.

Data Sources: A systematic search was performed on six databases (MEDLINE, EMBASE, AMED, Web of Sciences Core Collection, The Cochrane Library, and The Health Management Information Consortium), public repositories, and the websites of organizations involved in the reporting of MSK QIs.

Study Selection: Potential QI sources were screened for relevance using an a priori criteria.

Harnessing digital footprint data for population health: a discussion on collaboration, challenges and opportunities in the UK.

Digital footprint data are inspiring a new era in population health and well-being research. Linking these novel data with other datasets is critical for future research wishing to use these data for the public good. In order to succeed, successful collaboration among industry, academics and policy-makers is vital.

Characteristics and academic career outcomes of Godina Fellowship recipients.

The American Society for Reconstructive Microsurgery (ASRM) sponsors the Godina Fellowship to expand the careers of talented early career microsurgeons. This study characterizes the scholarly impact and academic career outcomes of Godina Fellows. The ASRM provided a list of Godina Fellows since program inception (1993 - 2020).

Efficacy and outcomes of a highland prehospital trauma response team.

Background And Aims: The Scottish Highlands face unique prehospital care challenges due to population dispersity, mountainous terrain, seasonal weather, and higher trauma burden compared to the nearest Major Trauma Centres (MTCs) as highlighted by the Scottish Trauma Audit Group (STAG). Primary road/air transfer from scene to nearest designated MTC averages 1-5 hours, making prompt and informed utilisation of prehospital and in-hospital resources within the Highlands critical - comparative to other UK metropolitan regions where the trauma population majority lay within 20-45 minute transfer windows. This paper reviews the Highland pre-hospital immediate care and trauma (PICT) Team's trauma response through a retrospective review of PICT patient report forms (PRFs).

Application of low-density polyethylene (LDPE) passive samplers for monitoring PAHs in groundwater.

Equilibrium passive sampling continues to find increasing use for performing in situ assessments and monitoring of hydrophobic organic compounds (HOCs). Although this method has been successfully used in several field studies including open surface waters and sediments, comparatively, their use in groundwater has been very limited. In this study, low-density polyethylene (LDPE) passive samplers were deployed for 80 days in three groundwater wells contaminated with polycyclic aromatic hydrocarbons (PAHs).

Medium vessel occlusion thrombectomy: Single center experience using the 3 MAX catheter.

Introduction: Thrombectomy for medium vessel occlusion is a topic of great interest. We describe a single-center experience with the Penumbra 3-MAX aspiration catheter in stroke thrombectomy of medium vessel occlusion(MeVO). We investigated the use of 3-MAX as a de-novo first pass catheter and as a rescue aspiration device following attempted thrombectomy with other devices.