Changes in benign cell populations in cases of cervical cancer and its precursors.

In two totally independent experiments, typical intermediate cells were visually selected by experienced cytotechnicians trained in the analysis of monodisperse Papanicolaou-stained ectocervical smears. The smears were carefully diagnosed per se and in correlation with routine smears from the same patients. For specimens of classes exhibiting tumor cells, the diagnosis was histologically verified.

Computer recognition of ectocervical cells: image features.

Machine recognition of ectocervical cells has been achieved with good classification success by a number of research groups. Even though a substantial number of cell image features have been introduced, only a moderate number are required for classification. For them, definitions and measures of their discriminatory potential are presented.

[Prolonged fever and latent tuberculous foci].

Two cases of prolonged fever are reported. In the first case a tuberculous abscess of the liver was considered after an ultrasonic examination of the periphery of an hepatic calcification discovered many years ago; a right hepatectomy confirmed the diagnosis. The second patient was treated twenty years ago for a tuberculous exsudative peritonitis.

Estimation of the performance of an array-processor oriented system for automatic Pap smear analysis.

The rapid progress in computer technology makes possible the automatic analysis of thousands of cells on a slide in the field of automatic uterine cancer cytology. Our approach starts with the high-resolution scanning of visually selected and classified single cells determining the training set for discriminant analysis. On the basis of more than 15 morphologic and textural features measured, correct classification results of 95% are reached.

Binding and inhibitory effect of 2-heptyl-4-hydroxyquinoline-N-oxide in the presence of ubiquinone-3 in Saccharomyces cerevisiae.

1. 2-Heptyl-4-hydroxyquinoline-N-oxide (HpHOQnO) binds to oxidized mitochondria of Saccharomyces cerevisiae with a dissociation constant of 5 x 10(-8) M and with a ratio of 1 mol per mol cytochrome b. 2.

Oral cholecystography: is the fatty meal always necessary?

In our study we have collected 1000 consecutive cases of oral cholecystographic opacification of the gall-bladder and common bile duct; occasionally a complimentary intra-venous cholangiography had also been carried out. In 360 cases there was disease of the gall-bladder or a faint opacification of the common bile duct was abnormal in only three cases, which is a rate of 0,47%. Therefore the fatty meal after oral cholecystography should not be done in each case but only if there is a presumptive diagnosis of pancreatic disease, if there is pancreatic calcification, or if surgery has been previously performed on the biliary tract or duodenum.

[Oral cholecystography: is the fatty meal compulsory (author's transl)].

An investigation on 1000 cases of oral cholecystography allowed us to collect 640 non pathologic opacifications of the gallblader and among them only 3 cases of pathological common bile ducts (0,47 percent). Consequently when the gallbladder appears normal on the oral cholecystography, the fatty meal seems to be non compulsory but only when clinical findings are in favor of a pancreatic disease or if there are pancreatic calcifications or if surgery has been performed anteriorly on the bile ducts, the liver or the pancreas.

Progress report of the TUDAB project for automated cancer cell detection.

Two methods for high resolution cell image data acquisition are applied routinely. Cells are either scanned by a computer controlled fast scanning microscope photometer (SMP) or a TV-camera. The software system for digital image analysis was completely revised and implemented on the PR 330 minicomputer.

Differential effects of ethnic membership, sex, and occupation on the California Psychological Inventory.

This study investigated the effects of race, sex, and occupation on college students' responses to the California Psychological Inventory. Analyses of variance of the standard CPI scales indicated numerous race, sex, and race X sex effects. A comparison of the results of factor analyses of the responses of black and white subjects (within each sex) indicated a similarity in factor structure between the two female groups, but not for the two male groups.

Experimental Coxiella burnetii infection of guinea pigs and mice.

The susceptibility of five inbred strains of mice, designated DBA/1J, DBA/2J, C57BL/6J, Balf/CJ, and AKR/J, as well as outbred Hartley and Moen-Chase guinea pigs to infection with Coxiella burnetii by several routes was studied. The DBA/2J mice were more susceptible to infection and had higher mortality rates than other strains of mice. Guinea pigs were more susceptible to infection than mice.

Fibrosarcoma in a white-tailed deer.

A large, rapidly growing subcutaneous fibrosarcoma was observed on the head of an aged male white-tailed deer (Odocoileus virginianus) from Frederick County, Maryland. Although there was no evidence of distant metastasis, the large neoplastic mass had extensively invaded the osseous supraorbital process, and had several small satellite nodules nearby.

Personality patterns of drug abusers as shown by MMPI profiles.

MMPI and 16 PF patterns of a group of drug abusers who were participating in a voluntary VA Drug Abuse Program were investigated. The MMPI profiles of 91 male veterans who ranged in age from 18-45 years were classified according to two-point code types. A comparison was made of the most frequently occurring code types among drug abusers, medical patients, and psychiatric patients.

Studies on Macaca mulatta infected with Rocky Mountain spotted fever.

Acid-base alterations and changes in other selected serum constituents (free fatty acids, triglycerides, cholesterol, copper, cortisol, alpha1-acid glycoprotein, haptoglobin, and albumin) were measured during a study of Rocky Mountain spotted fever in 16 male rhesus macaques. Blood samples were taken from nonanesthetized macaques conditioned to repeated handling. Arterial pH increased and PCO2 decreased during the febrile period.

Appearance of cellular and humoral immunity in guinea pigs after infection with Coxiella burnetii administered in small-particle aerosols.

The development of humoral and cell-mediated immune responses was studied in guinea pigs infected with Coxiella burnetti administered in small-particle aerosols. Direct macrophage migration inhibition was observed in cultured peritoneal exudate cells as early as 3 days after exposure. Maximum inhibition of macrophages cultured with phase I or II antigen occurred 14 to 21 days postexposure and persisted through 35 days.

Extrachromosomal inheritance in Schizosaccharomyces pombe. III. Isolation and characterization of paromomycin-resistant mutants.

In the antimycin--resistant mutant anar-8 of the fission yeast Schizosaccharomyces pombe (Sch.p.) spontaneous mutants were isolated showing high resistance to the aminoglycoside antibiotic paromomycin.

Second order factors in the California Psychological Inventory.

In order to further specify the structure of the California Psychological Inventory (CPI), correlations among the first order factors of the CPI were factor analyzed, yielding two second order factors. These factors were described, and were named General Adjustment and Social Sensitivity, respectively. The second order configuration of CPI scales appeared to be consistent with other research done on the scales.