Oxygen is the most common treatment for newborns in need of respiratory support. However, oxygen can cause tissue injury through reactive oxygen species formation, especially in premature infants with reduced antioxidant defences, and may result in short-term and long-term toxic effects in multiple organ systems. Although most hospitals have the capability to tightly control oxygen delivery to hospitalised neonates, in many circumstances, the need is overlooked during infant transport.
View Article and Find Full Text PDFObjectives: To compare extubation failure rate between the heated humidified high-flow nasal cannula (HHHFNC) and continuous positive airway pressure (CPAP) groups.
Methods: Intubated infants with gestational age (GA) <32 wk, who were ready to extubate, were randomized to receive respiratory support with either CPAP or HHHFNC after extubation. In CPAP group, nasal mask CPAP with preset pressure and fraction of inspired oxygen (FiO) equal to positive end-expiratory pressure (PEEP) and FiO of ventilator before extubation was applied.
Objective: To determine the efficacy of polyethylene plastic draping in preventing hypothermia during umbilical catheterization.
Methods: A randomized controlled trial was conducted in newborns who required umbilical catheterization. A sterile polyethylene plastic sheet covering the procedural field was used in the plastic group, and a sterile conventional cotton drape was used in the control group.